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Successful Management of Lichen Myxedematosus: Report of a Case

Successful Management of Lichen Myxedematosus: Report of a Case Abstract • Radiation therapy led to local resolution of a case of lichen myxedematosus, which, to our knowledge, is the first reported successful treatment of the disease by radiation therapy. Radiation therapy is only the second therapeutic modality that is effective in the treatment of lichen myxedematosus. We propose specific criteria for the diagnosis of lichen myxedematosus to facilitate future studies into the nature of this disease. (Arch Dermatol 112:67-69, 1976) References 1. Dubreuilh W: Fibromes miliaries follicularies: Sclerodermis consecutive . Arch Dermatol Syph 7:569-570, 1906. 2. Gottron HA: Skleromyxodem (eine eigenartige Erscheinangys form von Myxothesaurodermis) . Arch Derm Syph Berlin 199:71-91, 1954.Crossref 3. Fowlkes RW, Blaylock WK, Mullinax F: Immunologic studies in lichen myxedematosus . Arch Dermatol 95:370-374, 1967.Crossref 4. Perry HO, Montgomery H, Stickney JM: Further observations on lichen myxedematosus . Ann Intern Med 53:955-969, 1960.Crossref 5. Verhov JL: Scleromyxoedema: A variant of lichen myxedematosus . Br J Dermatol 81:873, 1969. 6. Wigley JEM, Rees DL, Symmers WSTC: Lichen myxedematosus . Br J Dermatol 69:408-410, 1957.Crossref 7. Montgomery H, Underwood LJ: Lichen myxedematosus: Differentiation from cutaneous myxedemas or mucoid states . J Invest Dermatol 20:213-236, 1953. 8. Dalton JE, Seidell MA: Studies on lichen myxedematosus: Papular mucinosis . Arch Dermatol Syph 67:194-209, 1953.Crossref 9. Feldman P, Shapiro L, Pick AI, et al: Scleromyxedema: A dramatic response to melphalan . Arch Dermatol 99:51-56, 1969.Crossref 10. Degos R: Anomalies globuliniques dans les mucinoses cutances . Bull Soc Fr Dermatol Syphiligr 77:579-591, 1970. 11. Traenkle HL: X-ray induced skin cancer in man , in Urbach F (ed): National Cancer Institute Monograph 10 , 1967, pp 423-432. 12. Court-Brown WM, Doll R: Mortality from cancer and other causes after radiotherapy for ankylosing spondylitis . Br Med J 2:1327-1332, 1965.Crossref 13. Sauders TS, Montgomery H: Chronic roentgen and radium dermatitis . JAMA 100:23-28, 1938.Crossref 14. Crawley EP, Lupton CH, Wheeler CE, et al: Examination of normal and myxedematosus skin . Arch Dermatol 76:537-544, 1957.Crossref 15. McCarthy JY, Osserman E, Lombardo PC, et al: An abnormal serum globulin in lichen myxedematosus . Arch Dermatol 89:446-450, 1964.Crossref 16. Lawrence DA, Tye MJ, Liss M: Chemical analysis of the basic immunoglobulin in papular mucinosis . Immunochemistry 9:41-49, 1972.Crossref 17. Wells JV, Fudenberg HH, Epstein WL: Idiotypic determinants on the monoclonal immunoglobulins associated with papular mucinosis . J Immunol 108:977-983, 1972. 18. Lai A Fat RFM, Suurmond D, Rádl J, et al: Scleromyxoedema (lichen myxedematosus) associated with a paraprotein, IgG 1 of type kappa . Br J Dermatol 88:107-116, 1973.Crossref 19. Piper W, Hardmeier T, Schäfer E: Das Skleromyxödem Arndt-Gottron: Eine paraproteinämische Erkrankung . Schweiz Med Wochenschr 97:829-838, 1967. 20. Fudenberg HH, Epstein WL, Shuster J, et al: Diagnostic paraprotein in papular mucinosis . Bibl Haematol 29:318-321, 1968. 21. Shapiro CM, Fretzin D, Morris S: Papular mucinosis . JAMA 214:2052-2054, 1970.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Successful Management of Lichen Myxedematosus: Report of a Case

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References (25)

Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1976.01630250031009
Publisher site
See Article on Publisher Site

Abstract

Abstract • Radiation therapy led to local resolution of a case of lichen myxedematosus, which, to our knowledge, is the first reported successful treatment of the disease by radiation therapy. Radiation therapy is only the second therapeutic modality that is effective in the treatment of lichen myxedematosus. We propose specific criteria for the diagnosis of lichen myxedematosus to facilitate future studies into the nature of this disease. (Arch Dermatol 112:67-69, 1976) References 1. Dubreuilh W: Fibromes miliaries follicularies: Sclerodermis consecutive . Arch Dermatol Syph 7:569-570, 1906. 2. Gottron HA: Skleromyxodem (eine eigenartige Erscheinangys form von Myxothesaurodermis) . Arch Derm Syph Berlin 199:71-91, 1954.Crossref 3. Fowlkes RW, Blaylock WK, Mullinax F: Immunologic studies in lichen myxedematosus . Arch Dermatol 95:370-374, 1967.Crossref 4. Perry HO, Montgomery H, Stickney JM: Further observations on lichen myxedematosus . Ann Intern Med 53:955-969, 1960.Crossref 5. Verhov JL: Scleromyxoedema: A variant of lichen myxedematosus . Br J Dermatol 81:873, 1969. 6. Wigley JEM, Rees DL, Symmers WSTC: Lichen myxedematosus . Br J Dermatol 69:408-410, 1957.Crossref 7. Montgomery H, Underwood LJ: Lichen myxedematosus: Differentiation from cutaneous myxedemas or mucoid states . J Invest Dermatol 20:213-236, 1953. 8. Dalton JE, Seidell MA: Studies on lichen myxedematosus: Papular mucinosis . Arch Dermatol Syph 67:194-209, 1953.Crossref 9. Feldman P, Shapiro L, Pick AI, et al: Scleromyxedema: A dramatic response to melphalan . Arch Dermatol 99:51-56, 1969.Crossref 10. Degos R: Anomalies globuliniques dans les mucinoses cutances . Bull Soc Fr Dermatol Syphiligr 77:579-591, 1970. 11. Traenkle HL: X-ray induced skin cancer in man , in Urbach F (ed): National Cancer Institute Monograph 10 , 1967, pp 423-432. 12. Court-Brown WM, Doll R: Mortality from cancer and other causes after radiotherapy for ankylosing spondylitis . Br Med J 2:1327-1332, 1965.Crossref 13. Sauders TS, Montgomery H: Chronic roentgen and radium dermatitis . JAMA 100:23-28, 1938.Crossref 14. Crawley EP, Lupton CH, Wheeler CE, et al: Examination of normal and myxedematosus skin . Arch Dermatol 76:537-544, 1957.Crossref 15. McCarthy JY, Osserman E, Lombardo PC, et al: An abnormal serum globulin in lichen myxedematosus . Arch Dermatol 89:446-450, 1964.Crossref 16. Lawrence DA, Tye MJ, Liss M: Chemical analysis of the basic immunoglobulin in papular mucinosis . Immunochemistry 9:41-49, 1972.Crossref 17. Wells JV, Fudenberg HH, Epstein WL: Idiotypic determinants on the monoclonal immunoglobulins associated with papular mucinosis . J Immunol 108:977-983, 1972. 18. Lai A Fat RFM, Suurmond D, Rádl J, et al: Scleromyxoedema (lichen myxedematosus) associated with a paraprotein, IgG 1 of type kappa . Br J Dermatol 88:107-116, 1973.Crossref 19. Piper W, Hardmeier T, Schäfer E: Das Skleromyxödem Arndt-Gottron: Eine paraproteinämische Erkrankung . Schweiz Med Wochenschr 97:829-838, 1967. 20. Fudenberg HH, Epstein WL, Shuster J, et al: Diagnostic paraprotein in papular mucinosis . Bibl Haematol 29:318-321, 1968. 21. Shapiro CM, Fretzin D, Morris S: Papular mucinosis . JAMA 214:2052-2054, 1970.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Jan 1, 1976

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