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Subcutaneous Nodules in a Patient With Hydrocephalus

Subcutaneous Nodules in a Patient With Hydrocephalus Report of a case A 32-year-old woman presented with a 1-year history of hypopigmented nodules on her trunk and extremities. One month earlier, she had been seen by the neurosurgery service for progressively severe headaches. Magnetic resonance imaging showed obstructive hydrocephalus, and an intraventricular shunt was placed. Physical examination revealed hypopigmented, indurated 1- to 2-cm nodules distributed on the patient's face, trunk, and extremities (Figure 1). The results of the following laboratory tests were normal: chemistry panel, hematocrit, serum calcium levels, and urinalysis. Liver enzyme and angiotensin-converting enzyme levels were elevated. An electrocardiogram showed normal sinus rhythm. A 3-mm punch biopsy specimen of skin was obtained from the patient's arm (Figure 2). Figure 1. View LargeDownload Figure 2. View LargeDownload What is your diagnosis? http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 2002 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.138.2.259
Publisher site
See Article on Publisher Site

Abstract

Report of a case A 32-year-old woman presented with a 1-year history of hypopigmented nodules on her trunk and extremities. One month earlier, she had been seen by the neurosurgery service for progressively severe headaches. Magnetic resonance imaging showed obstructive hydrocephalus, and an intraventricular shunt was placed. Physical examination revealed hypopigmented, indurated 1- to 2-cm nodules distributed on the patient's face, trunk, and extremities (Figure 1). The results of the following laboratory tests were normal: chemistry panel, hematocrit, serum calcium levels, and urinalysis. Liver enzyme and angiotensin-converting enzyme levels were elevated. An electrocardiogram showed normal sinus rhythm. A 3-mm punch biopsy specimen of skin was obtained from the patient's arm (Figure 2). Figure 1. View LargeDownload Figure 2. View LargeDownload What is your diagnosis?

Journal

Archives of DermatologyAmerican Medical Association

Published: Feb 1, 2002

Keywords: hydrocephalus,subcutaneous nodules

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