Abstract • A patient had an evolving hematologic disorder, accompanied by tender, red, subcutaneous nodules. Histologically, there were dense neutrophilic infiltrates confined to the subcutaneous adipose tissue. Three months later, a typical episode of acute febrile neutrophilic dermatosis (ND) developed in the patient, and she was found to have acute myeloid leukemia. In addition to the dermis, the neutrophilic infiltrates of ND occasionally involve the subcutis. As seen in our patient, the infiltrates are rarely limited to the subcutaneous tissue. (Arch Dermatol 1983;119:610-611) References 1. Sweet RD: An acute febrile neutrophilic dermatosis . Br J Dermatol 1964;76:349-356.Crossref 2. Costello MJ, Canizares O, Montague M III, et al: Cutaneous manifestations of myelogenous leukemia . Arch Dermatol 1955;71:605-614.Crossref 3. Crow KD, Kerdel-Vegas F, Rook A: Acute febrile neutrophilic dermatosis: Sweet's syndrome . Dermatologica 1969;139:123-134.Crossref 4. Chmel H, Armstrong D: Acute febrile neutrophilic dermatosis: Sweet's syndrome . South Med J 1978;71:1350-1352.Crossref 5. Cooper PH, Innes DJ Jr, Greer KE: Acute febrile neutrophilic dermatosis (Sweet's syndrome) and myeloproliferative disorders . Cancer , in press.
Archives of Dermatology – American Medical Association
Published: Jul 1, 1983