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SUBCUTANEOUS INJECTIONS OF PROCAINE PENICILLIN IN TREATMENT OF CHRONIC SYCOSIS VULGARIS AND HIDRADENITIS SUPPURATIVA AXILLARIS

SUBCUTANEOUS INJECTIONS OF PROCAINE PENICILLIN IN TREATMENT OF CHRONIC SYCOSIS VULGARIS AND... Abstract Sycosis vulgaris, a purulent folliculitis and perifolliculitis of staphylococcic origin, and hidradenitis suppurativa, an inflammatory disease in apocrine gland-bearing areas which is sometimes referred to as a staphyloderma, have several things in common: the infectious agent, the extreme chronicity and the frequent remissions and relapses. In addition, both these conditions are deep infections, for in chronic sycosis vulgaris1 the pathological process may involve the entire cutis and in hidradenitis suppurativa2 the infection usually spreads throughout the subcutaneous tissues. In the later stages of hidradenitis suppurativa suppuration persists and extends into the deep layers of the subcutaneous tissue with the formation of extensive sinus tracts. The methods of treating these disorders are legion, and the prognosis not always favorable. George C. Andrews3 in discussing the treatment of hidradenitis suppurativa axillaris advises, first, roentgen therapy as the therapy of choice and, second, in cases in which there is no response to irradiation, surgical excision of the affected skin area and replacement with a full thickness graft. References 1. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , ed. 7, Philadelphia, Lea & Febiger, 1948, p. 1386. 2. Ormsby and Montgomery,1 p. 1276. 3. Andrews, G. C.: Diseases of the Skin for Practitioners and Students , ed. 3, Philadelphia, W. B. Saunders Company, 1946, pp. 790-791. 4. Ormsby and Montgomery, 1 p. 1277. 5. Alidase,® the brand of hyaluronidase used, was supplied for this work by courtesy of G. D. Searle & Co. 6. Crysticillin® (Squibb), the product used, is a dry crystalline procaine penicillin G combined with suitable and harmless dispersing and stabilizing agents. It contains no oil or wax. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

SUBCUTANEOUS INJECTIONS OF PROCAINE PENICILLIN IN TREATMENT OF CHRONIC SYCOSIS VULGARIS AND HIDRADENITIS SUPPURATIVA AXILLARIS

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Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1951.01570030094014
Publisher site
See Article on Publisher Site

Abstract

Abstract Sycosis vulgaris, a purulent folliculitis and perifolliculitis of staphylococcic origin, and hidradenitis suppurativa, an inflammatory disease in apocrine gland-bearing areas which is sometimes referred to as a staphyloderma, have several things in common: the infectious agent, the extreme chronicity and the frequent remissions and relapses. In addition, both these conditions are deep infections, for in chronic sycosis vulgaris1 the pathological process may involve the entire cutis and in hidradenitis suppurativa2 the infection usually spreads throughout the subcutaneous tissues. In the later stages of hidradenitis suppurativa suppuration persists and extends into the deep layers of the subcutaneous tissue with the formation of extensive sinus tracts. The methods of treating these disorders are legion, and the prognosis not always favorable. George C. Andrews3 in discussing the treatment of hidradenitis suppurativa axillaris advises, first, roentgen therapy as the therapy of choice and, second, in cases in which there is no response to irradiation, surgical excision of the affected skin area and replacement with a full thickness graft. References 1. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , ed. 7, Philadelphia, Lea & Febiger, 1948, p. 1386. 2. Ormsby and Montgomery,1 p. 1276. 3. Andrews, G. C.: Diseases of the Skin for Practitioners and Students , ed. 3, Philadelphia, W. B. Saunders Company, 1946, pp. 790-791. 4. Ormsby and Montgomery, 1 p. 1277. 5. Alidase,® the brand of hyaluronidase used, was supplied for this work by courtesy of G. D. Searle & Co. 6. Crysticillin® (Squibb), the product used, is a dry crystalline procaine penicillin G combined with suitable and harmless dispersing and stabilizing agents. It contains no oil or wax.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Mar 1, 1951

References