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SUBACUTE MILIARY TUBERCULOSIS

SUBACUTE MILIARY TUBERCULOSIS While the literature on acute miliary tuberculosis in children in the United States is extensive, the reports on the subacute and chronic forms are rather meager. Greengard reported fifty-four cases of miliary tuberculosis in children from the Cook County Hospital in 1925, all of them fatal, only 9 per cent of the children surviving from three to four months. The pathologic explanation for the almost invariable fatality of miliary tuberculosis is as follows: At successive times, there occur discharges of tubercle bacilli into the blood stream from some primary focus, usually a lymph node. This is borne out by the resultant crops of tubercles, the tubercles of each crop being of approximately the same size. Successively repeated discharges of tubercle bacilli into the blood stream are almost invariably the rule, which accounts for the generalized infection that rapidly overwhelms the organism. It is conceivable that if the primary focus is http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

SUBACUTE MILIARY TUBERCULOSIS

American journal of diseases of children , Volume 40 (6) – Dec 1, 1930

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Publisher
American Medical Association
Copyright
Copyright © 1930 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1930.01940060109010
Publisher site
See Article on Publisher Site

Abstract

While the literature on acute miliary tuberculosis in children in the United States is extensive, the reports on the subacute and chronic forms are rather meager. Greengard reported fifty-four cases of miliary tuberculosis in children from the Cook County Hospital in 1925, all of them fatal, only 9 per cent of the children surviving from three to four months. The pathologic explanation for the almost invariable fatality of miliary tuberculosis is as follows: At successive times, there occur discharges of tubercle bacilli into the blood stream from some primary focus, usually a lymph node. This is borne out by the resultant crops of tubercles, the tubercles of each crop being of approximately the same size. Successively repeated discharges of tubercle bacilli into the blood stream are almost invariably the rule, which accounts for the generalized infection that rapidly overwhelms the organism. It is conceivable that if the primary focus is

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Dec 1, 1930

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