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Study of the Food and Drug Administration Files on Propecia

Study of the Food and Drug Administration Files on Propecia COMMENTARY Study of the Food and Drug Administration Files on Propecia Dosages, Side Effects, and Recommendations ECENTLY, the Food and years, yet the predominant users are Thus, a 20 times smaller dose than Drug Administration expected to be males in their 30s. that recommended had the same ef- (FDA) approved the Use of the drug must be continued fect on the DHT. use of the drug finas- indefinitely if new hair growth is to A similar dose dependence was R teride (Proscar) under continue over one’s lifetime. seen for the serum DHT level a new name, Propecia, for treatment A key question for hair loss (Figure 2); the effect was no dif- of male pattern baldness. Although the that needs resolution is the dose of ferent with doses above 0.2 mg. generic term for the drug is finasteride, Propecia that should be used. In Dose dependence also occurs in it is marketed under these 2 different prior Merck studies, it was found the accompanying rise in testoster- proprietary names. The Proscar pill is that, in measurements of prostate one levels, with about ⁄100 the 5-mg 5 mg and the Propecia pill, 1 mg. Pro- shrinkage, a 1-mg dose could http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Study of the Food and Drug Administration Files on Propecia

JAMA Dermatology , Volume 135 (3) – Mar 1, 1999

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Publisher
American Medical Association
Copyright
Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/archderm.135.3.257
Publisher site
See Article on Publisher Site

Abstract

COMMENTARY Study of the Food and Drug Administration Files on Propecia Dosages, Side Effects, and Recommendations ECENTLY, the Food and years, yet the predominant users are Thus, a 20 times smaller dose than Drug Administration expected to be males in their 30s. that recommended had the same ef- (FDA) approved the Use of the drug must be continued fect on the DHT. use of the drug finas- indefinitely if new hair growth is to A similar dose dependence was R teride (Proscar) under continue over one’s lifetime. seen for the serum DHT level a new name, Propecia, for treatment A key question for hair loss (Figure 2); the effect was no dif- of male pattern baldness. Although the that needs resolution is the dose of ferent with doses above 0.2 mg. generic term for the drug is finasteride, Propecia that should be used. In Dose dependence also occurs in it is marketed under these 2 different prior Merck studies, it was found the accompanying rise in testoster- proprietary names. The Proscar pill is that, in measurements of prostate one levels, with about ⁄100 the 5-mg 5 mg and the Propecia pill, 1 mg. Pro- shrinkage, a 1-mg dose could

Journal

JAMA DermatologyAmerican Medical Association

Published: Mar 1, 1999

References