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STUDIES OF TETANY

STUDIES OF TETANY It has for sometime been a matter of observation in this clinic, and no doubt elsewhere, that infants receiving calcium chlorid for relief of the symptoms of tetany will occasionally develop hyperpnea. In these instances a marked lowering of the plasma bicarbonate may be demonstrated. It is possible to explain an acid effect from the ingestion of calcium chlorid by assuming a more complete absorption of the chlorid ion (Cl-) than of the calcium ion (Ca + +) from the gastro-intestinal tract. The probability that a large part of the calcium will form insoluble phosphates and soaps, and, in consequence, escape absorption affords ground for this surmise. If this is the case the uncovered chlorid ion must be provided before absorption with other base derived from the carbonates and dibasic phosphates of the food. The effect on acid-base metabolism of an excess of the chlorid ion over the calcium ion absorbed should http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1923 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1923.01920060044004
Publisher site
See Article on Publisher Site

Abstract

It has for sometime been a matter of observation in this clinic, and no doubt elsewhere, that infants receiving calcium chlorid for relief of the symptoms of tetany will occasionally develop hyperpnea. In these instances a marked lowering of the plasma bicarbonate may be demonstrated. It is possible to explain an acid effect from the ingestion of calcium chlorid by assuming a more complete absorption of the chlorid ion (Cl-) than of the calcium ion (Ca + +) from the gastro-intestinal tract. The probability that a large part of the calcium will form insoluble phosphates and soaps, and, in consequence, escape absorption affords ground for this surmise. If this is the case the uncovered chlorid ion must be provided before absorption with other base derived from the carbonates and dibasic phosphates of the food. The effect on acid-base metabolism of an excess of the chlorid ion over the calcium ion absorbed should

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jun 1, 1923

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