Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Studies in Sickle Cell Anemia: XXVI. The Effects of Homozygous Sickle Cell Disease on the Onset of Menarche, Pregnancy, Fertility, Pubescent Changes, and Body Growth in Negro Subjects

Studies in Sickle Cell Anemia: XXVI. The Effects of Homozygous Sickle Cell Disease on the Onset... Abstract EARLIER clinical observations have suggested that patients with sickle cell disease tend to show an increased incidence of complications during labor,1,2 a tendency to lowered fertility,3,4 characteristic hypoplastic genitalia,5,6 eunuchoid habitus,6-11 and are often smaller than their nonanemic siblings.11,12 Studies previously reported by Michelson13 that the average age of menarche in Negroes (with a comparative study by Boas,14 Simmons and Greulich,15 on the age of menarche among white girls), was 12.94±1.1 years in the northern states and 13.68±1.4 years in the southern part of the United States. This variation in the onset in the different regions was believed to be due to a better socioeconomic status of Negroes in the north according to Michelson,13 Engelsman,16 and Gould and Gould.17 During the past three decades, the age of onset of puberty has decreased by ten months in Negroes and References 1. Woodard, D.; Beachman, D.; and Beachman, W.: Sickle Cell Disease and Pregnancy , Amer J Obstet Gynec 60:1217-1228, 1950. 2. Yater, W.M., and Mollari, M.: Pathology of Sickle Cell Anemia , JAMA 96:1671-1675, 1931.Crossref 3. Sodeman, W.A., and Burch, G.W.: Pregnancy in Active Sickle Cell Anemia , New Orleans Med Surg J 90:156-158, 1937. 4. Anderson, G.W., and Busby, T.: Sickle Cell Anemia and Pregnancy , Amer J Obstet Gynec 58:75-89, 1949. 5. Anderson, W.W., and Ware, R.L.: Sickle Cell Anemia , Amer J Dis Child 44:1055-1070, 1932. 6. Margolis, M.P.: Sickle Cell Anemia: A Composite Study and Survey , Medicine 30:357-443, 1951.Crossref 7. Winsor, T., and Burch, G.E.: Habitus of Patients With Active Sickle Cell Anemia of Long Duration , Arch Intern Med 76:47-53, 1954.Crossref 8. Winsor, T., and Burch, G.E.: Habitus of Patients With Sickle Cell Anemia , Hum Biol 16:99-113, 1944. 9. Sharpe, E.A., and Vander Heide, E.C.: Eunuchoid Habitus Associated With Sickle Cell Anemia and Sickling Trait , J Clin Endocr 4:505, 1944.Crossref 10. Whitten, C.: Growth Status of Children With Sickle Cell Anemia , Amer J Dis Child 102:355-364, 1961. 11. Trowell, H.C.; Raper, A.B.; and Welbourne, H.F.: The Natural History of Homozygous Sickle-Cell Anemia in Central Africa , Quart J Med 26:401-422, 1957. 12. Green, O.C.: Growth in Sickle Cell Anemia , Nutr Rev 20:237-238, 1962. 13. Michelson, N.: Studies in Physical Development of Negroes, Onset of Puberty , Amer J Phys Anthrop 2:151-166, 1944.Crossref 14. Franz, B.: Studies in Growth of White Children , Hum Biol 4:307-360, 1932. 15. Simmons, K., and Greulich, W.W.: Menarcheal Age and the Height, Weight, and Skeletal Age of Girls Ages 7-17 Years , J Pediat 22:518-548, 1943.Crossref 16. Engleman, G.J.: Age of First Menstruation on the North American Continent , New York Med J 75:221-228, 270-274, 1902. 17. Gould, H.N., and Gould, M.R.: Age of First Menstruation of Mothers and Daughters , JAMA 98: 1349-1352, 1932.Crossref 18. Wilkins, L.: The Diagnosis and Treatment of Endocrine Disorders in Childhood and Adolescence , ed 2, Springfield, Ill: Charles C Thomas, Publisher, 1960. 19. Rafeinstein, E.C., Jr.; Kinsell, L.M.; and Albright, F.: Observations on the Use of Serum Phosphorous Level as an Index of Pituitary Growth Hormone Activity: The Effect of Estrogen in Aeromegaly , J Clin Endocr 6:470, 1946. 20. Diggs, L.W.; Pulliam, H.M.; and King, J.C.: Bone Changes in SCA , Southern Med J 30:247, 1937.Crossref 21. Bartter, F.C.: Osteoporosis: Seminar on Bone Disease , Amer J Med 22:797-805, 1957.Crossref 22. Soffer, L.J.; Fulterweit, W.; and Galvaneschi, J.: A Gonadotropin Inhibiting Substance in the Urine of Normal Young Children , J Clin Endocr 21: 1267-1271, 1961.Crossref 23. Peirce, L.E., and Rath, C.E.: Evidence of Folic Acid Deficiency in the Genesis of Anemic Sickle Cell Crisis , Blood 20:19-32, 1962. 24. Oliner, H., and Keller, P.: Megaloblastic Erythropoiesis and Acquired Hemolysis in Sickle Cell Anemia , New Eng J Med 261:1, 19-22, 1959.Crossref 25. Watson-Williams, E.J.: Folic Acid Deficiency in Sickle Cell Anemia , E Afr Med J 39:213-221, 1962. 26. Pearson, H.A., and Cobb, W.T.: Folic Acid Studies in Sickle Cell Anemia , J Lab Clin Med 64: 913-921, 1964. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Studies in Sickle Cell Anemia: XXVI. The Effects of Homozygous Sickle Cell Disease on the Onset of Menarche, Pregnancy, Fertility, Pubescent Changes, and Body Growth in Negro Subjects

Download PDF
8 pages

Loading next page...
 
/lp/american-medical-association/studies-in-sickle-cell-anemia-xxvi-the-effects-of-homozygous-sickle-26S04ivJ0W

References (28)

Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1966.02090080075005
Publisher site
See Article on Publisher Site

Abstract

Abstract EARLIER clinical observations have suggested that patients with sickle cell disease tend to show an increased incidence of complications during labor,1,2 a tendency to lowered fertility,3,4 characteristic hypoplastic genitalia,5,6 eunuchoid habitus,6-11 and are often smaller than their nonanemic siblings.11,12 Studies previously reported by Michelson13 that the average age of menarche in Negroes (with a comparative study by Boas,14 Simmons and Greulich,15 on the age of menarche among white girls), was 12.94±1.1 years in the northern states and 13.68±1.4 years in the southern part of the United States. This variation in the onset in the different regions was believed to be due to a better socioeconomic status of Negroes in the north according to Michelson,13 Engelsman,16 and Gould and Gould.17 During the past three decades, the age of onset of puberty has decreased by ten months in Negroes and References 1. Woodard, D.; Beachman, D.; and Beachman, W.: Sickle Cell Disease and Pregnancy , Amer J Obstet Gynec 60:1217-1228, 1950. 2. Yater, W.M., and Mollari, M.: Pathology of Sickle Cell Anemia , JAMA 96:1671-1675, 1931.Crossref 3. Sodeman, W.A., and Burch, G.W.: Pregnancy in Active Sickle Cell Anemia , New Orleans Med Surg J 90:156-158, 1937. 4. Anderson, G.W., and Busby, T.: Sickle Cell Anemia and Pregnancy , Amer J Obstet Gynec 58:75-89, 1949. 5. Anderson, W.W., and Ware, R.L.: Sickle Cell Anemia , Amer J Dis Child 44:1055-1070, 1932. 6. Margolis, M.P.: Sickle Cell Anemia: A Composite Study and Survey , Medicine 30:357-443, 1951.Crossref 7. Winsor, T., and Burch, G.E.: Habitus of Patients With Active Sickle Cell Anemia of Long Duration , Arch Intern Med 76:47-53, 1954.Crossref 8. Winsor, T., and Burch, G.E.: Habitus of Patients With Sickle Cell Anemia , Hum Biol 16:99-113, 1944. 9. Sharpe, E.A., and Vander Heide, E.C.: Eunuchoid Habitus Associated With Sickle Cell Anemia and Sickling Trait , J Clin Endocr 4:505, 1944.Crossref 10. Whitten, C.: Growth Status of Children With Sickle Cell Anemia , Amer J Dis Child 102:355-364, 1961. 11. Trowell, H.C.; Raper, A.B.; and Welbourne, H.F.: The Natural History of Homozygous Sickle-Cell Anemia in Central Africa , Quart J Med 26:401-422, 1957. 12. Green, O.C.: Growth in Sickle Cell Anemia , Nutr Rev 20:237-238, 1962. 13. Michelson, N.: Studies in Physical Development of Negroes, Onset of Puberty , Amer J Phys Anthrop 2:151-166, 1944.Crossref 14. Franz, B.: Studies in Growth of White Children , Hum Biol 4:307-360, 1932. 15. Simmons, K., and Greulich, W.W.: Menarcheal Age and the Height, Weight, and Skeletal Age of Girls Ages 7-17 Years , J Pediat 22:518-548, 1943.Crossref 16. Engleman, G.J.: Age of First Menstruation on the North American Continent , New York Med J 75:221-228, 270-274, 1902. 17. Gould, H.N., and Gould, M.R.: Age of First Menstruation of Mothers and Daughters , JAMA 98: 1349-1352, 1932.Crossref 18. Wilkins, L.: The Diagnosis and Treatment of Endocrine Disorders in Childhood and Adolescence , ed 2, Springfield, Ill: Charles C Thomas, Publisher, 1960. 19. Rafeinstein, E.C., Jr.; Kinsell, L.M.; and Albright, F.: Observations on the Use of Serum Phosphorous Level as an Index of Pituitary Growth Hormone Activity: The Effect of Estrogen in Aeromegaly , J Clin Endocr 6:470, 1946. 20. Diggs, L.W.; Pulliam, H.M.; and King, J.C.: Bone Changes in SCA , Southern Med J 30:247, 1937.Crossref 21. Bartter, F.C.: Osteoporosis: Seminar on Bone Disease , Amer J Med 22:797-805, 1957.Crossref 22. Soffer, L.J.; Fulterweit, W.; and Galvaneschi, J.: A Gonadotropin Inhibiting Substance in the Urine of Normal Young Children , J Clin Endocr 21: 1267-1271, 1961.Crossref 23. Peirce, L.E., and Rath, C.E.: Evidence of Folic Acid Deficiency in the Genesis of Anemic Sickle Cell Crisis , Blood 20:19-32, 1962. 24. Oliner, H., and Keller, P.: Megaloblastic Erythropoiesis and Acquired Hemolysis in Sickle Cell Anemia , New Eng J Med 261:1, 19-22, 1959.Crossref 25. Watson-Williams, E.J.: Folic Acid Deficiency in Sickle Cell Anemia , E Afr Med J 39:213-221, 1962. 26. Pearson, H.A., and Cobb, W.T.: Folic Acid Studies in Sickle Cell Anemia , J Lab Clin Med 64: 913-921, 1964.

Journal

American Journal of Diseases of Children – American Medical Association

Published: May 1, 1966

There are no references for this article.