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Stress in Health and Disease

Stress in Health and Disease This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract More than 40 years have elapsed since the concept of the general adaptation syndrome (GAS) was introduced by Selye in a letter to the editor of Nature. It has since been widely studied, leading to nearly 100,000 publications in the medical and lay press. The essence of the idea is that a wide variety of nonspecific stimuli provoke a relatively stereotyped pattern of response marked by increased adrenal cortical secretion or even adrenal cortical hypertrophy. Selye regards a "stressor" to be any stimulus capable of leading to "general adaptation." The phenomenon of adaptation has become of major importance to neurologists in understanding some of the relationships between the hypothalamus, other parts of the nervous system, and the adrenal cortex, both in terms of normal function and the pathogenesis of a wide variety of diseases. Selye intended this volume to be an encyclopedia dealing with many aspects of stress ranging from http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Stress in Health and Disease

Archives of Neurology , Volume 34 (3) – Mar 1, 1977

Stress in Health and Disease

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract More than 40 years have elapsed since the concept of the general adaptation syndrome (GAS) was introduced by Selye in a letter to the editor of Nature. It has since been widely studied, leading to nearly 100,000 publications in the medical and lay press. The essence of the idea is that a wide variety of nonspecific stimuli provoke a relatively...
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Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1977.00500150088024
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract More than 40 years have elapsed since the concept of the general adaptation syndrome (GAS) was introduced by Selye in a letter to the editor of Nature. It has since been widely studied, leading to nearly 100,000 publications in the medical and lay press. The essence of the idea is that a wide variety of nonspecific stimuli provoke a relatively stereotyped pattern of response marked by increased adrenal cortical secretion or even adrenal cortical hypertrophy. Selye regards a "stressor" to be any stimulus capable of leading to "general adaptation." The phenomenon of adaptation has become of major importance to neurologists in understanding some of the relationships between the hypothalamus, other parts of the nervous system, and the adrenal cortex, both in terms of normal function and the pathogenesis of a wide variety of diseases. Selye intended this volume to be an encyclopedia dealing with many aspects of stress ranging from

Journal

Archives of NeurologyAmerican Medical Association

Published: Mar 1, 1977

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