ARTICLE Sterile Cerebrospinal Fluid Pleocytosis in Young Febrile Infants With Urinary Tract Infections David Schnadower, MD, MPH; Nathan Kuppermann, MD, MPH; Charles G. Macias, MD, MPH; Stephen B. Freedman, MDCM, MSc; Marc N. Baskin, MD; Paul Ishimine, MD; Camille Scribner, MD; Pamela Okada, MD; Heather Beach, MD; Blake Bulloch, MD; Dewesh Agrawal, MD; Mary Saunders, MD; Donna M. Sutherland, MD; Mercedes M. Blackstone, MD; Amit Sarnaik, MD; Julie McManemy, MD, MPH; Alison Brent, MD; Jonathan Bennett, MD; Jennifer M. Plymale, MD; Patrick Solari, MD; Deborah J. Mann, MD; Peter S. Dayan, MD, MSc; for the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics Objectives: To determine the prevalence of and to iden- events, time to defervescence, duration of parenteral tify risk factors for sterile cerebrospinal fluid (CSF) pleo- antibiotic treatment, and length of hospitalization). cytosis in a large sample of febrile young infants with uri- Results: A total of 214 of 1190 infants had sterile CSF pleo- nary tract infections (UTIs) and to describe the clinical cytosis (18.0%; 95% confidence interval, 15.9%-20.3%). courses of those patients. Only the peripheral white blood cell count was indepen- dently associated with sterile CSF pleocytosis, and pa- Design: Secondary
JAMA Pediatrics – American Medical Association
Published: Jul 1, 2011
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