Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Spontaneous Remission of Infantile Spasms With Hypsarhythmia

Spontaneous Remission of Infantile Spasms With Hypsarhythmia Abstract To the Editor.— Infantile spasms in the first year of life, with hypsarhythmia on EEG, are associated with a high incidence of retardation.1 A few such patients ultimately have normal intelligence and are free of seizures. The literature suggests that the likelihood of a good prognosis is enhanced by the early institution of therapy with corticotropin,2-5 particularly in the cryptogenic cases.The case presented here represents classic infantile spasms associated with hypsarhythmia. No medication was used, and a spontaneous remission occurred. Report of a Case.— A 7-month-old boy was first seen in consultation for frequent bursts of typical flexor spasms that had appeared when the patient was 2 months of age, associated with slowing of development. Family history, pregnancy, labor, delivery, patient's history, and patient's development before this were normal. He had had no immunizations. At 5 months of age, while still having the infantile spasms, an References 1. Swaiman KF, Wright FS: The Practice of Pediatric Neurology . St Louis, CV Mosby Co, 1975, vol 2, p 861. 2. Jeavons PM, Bower BD, Dimitrakqudi M: Long term prognosis in 150 cases of 'West Syndrome.' Epilepsia 1973;14:153-164.Crossref 3. Singer WD, Rabe EF, Haller JS: The effect of ACTH therapy on infantile spasms . J Pediatr 1980;96:485-489.Crossref 4. Pollack MA, Zion TE, Kellaway P: Long-term prognosis of patients with infantile spasms following ACTH therapy . Epilepsia 1979;20:255-260.Crossref 5. Matsumoto A, Watanabe K, Negoro T, et al: Long-term prognosis after infantile spasms: A statistical study of prognostic factors in 200 cases . Dev Med Child Neurol 1981;23:51-65.Crossref 6. Bray PF, Herbst JJ, Johnson DG, et al: Childhood gastroesophageal reflux: Neurologic and psychiatric syndromes mimicked . JAMA 1977;237:1342-1345.Crossref 7. Bachman DS: Use of valproic acid in treatment of infantile spasms . Arch Neurol , to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Spontaneous Remission of Infantile Spasms With Hypsarhythmia

Archives of Neurology , Volume 38 (12) – Dec 1, 1981

Spontaneous Remission of Infantile Spasms With Hypsarhythmia

Abstract

Abstract To the Editor.— Infantile spasms in the first year of life, with hypsarhythmia on EEG, are associated with a high incidence of retardation.1 A few such patients ultimately have normal intelligence and are free of seizures. The literature suggests that the likelihood of a good prognosis is enhanced by the early institution of therapy with corticotropin,2-5 particularly in the cryptogenic cases.The case presented here represents classic infantile spasms associated with...
Loading next page...
 
/lp/american-medical-association/spontaneous-remission-of-infantile-spasms-with-hypsarhythmia-pmU9KnItMH
Publisher
American Medical Association
Copyright
Copyright © 1981 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1981.00510120085020
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— Infantile spasms in the first year of life, with hypsarhythmia on EEG, are associated with a high incidence of retardation.1 A few such patients ultimately have normal intelligence and are free of seizures. The literature suggests that the likelihood of a good prognosis is enhanced by the early institution of therapy with corticotropin,2-5 particularly in the cryptogenic cases.The case presented here represents classic infantile spasms associated with hypsarhythmia. No medication was used, and a spontaneous remission occurred. Report of a Case.— A 7-month-old boy was first seen in consultation for frequent bursts of typical flexor spasms that had appeared when the patient was 2 months of age, associated with slowing of development. Family history, pregnancy, labor, delivery, patient's history, and patient's development before this were normal. He had had no immunizations. At 5 months of age, while still having the infantile spasms, an References 1. Swaiman KF, Wright FS: The Practice of Pediatric Neurology . St Louis, CV Mosby Co, 1975, vol 2, p 861. 2. Jeavons PM, Bower BD, Dimitrakqudi M: Long term prognosis in 150 cases of 'West Syndrome.' Epilepsia 1973;14:153-164.Crossref 3. Singer WD, Rabe EF, Haller JS: The effect of ACTH therapy on infantile spasms . J Pediatr 1980;96:485-489.Crossref 4. Pollack MA, Zion TE, Kellaway P: Long-term prognosis of patients with infantile spasms following ACTH therapy . Epilepsia 1979;20:255-260.Crossref 5. Matsumoto A, Watanabe K, Negoro T, et al: Long-term prognosis after infantile spasms: A statistical study of prognostic factors in 200 cases . Dev Med Child Neurol 1981;23:51-65.Crossref 6. Bray PF, Herbst JJ, Johnson DG, et al: Childhood gastroesophageal reflux: Neurologic and psychiatric syndromes mimicked . JAMA 1977;237:1342-1345.Crossref 7. Bachman DS: Use of valproic acid in treatment of infantile spasms . Arch Neurol , to be published.

Journal

Archives of NeurologyAmerican Medical Association

Published: Dec 1, 1981

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month