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Spontaneous Fractures in Tuberculous Meningitis

Spontaneous Fractures in Tuberculous Meningitis Abstract Spontaneous fractures of the sternum have been described in adult patients with tuberculosis.1 No evidence of intrinsic bone disease has been found and no disturbance of calcium or phosphorus metabolism was noted in these cases. Furthermore, the apparent high incidence of rib fractures in tuberculous patients2 raises the question of an effect of the infection on bony structures. However, up to now patients with tuberculosis are not considered particularly liable to decalcification, except insofar as unusually prolonged bed rest may lead to demineralization. The scope of this paper is to report on four patients, all of them infants, who during their treatment for tuberculous meningitis developed spontaneous fractures of the lower extremities without any evidence of localized tuberculous lesions on the areas of the fractures. We do not consider the factor of bed rest alone as constituting a satisfactory explanation for these fractures. Report of Cases Case 1.—A References 1. Bass, H. E., and Small, M. J.: Spontaneous Fracture of Sternum in Tuberculosis , J. A. M. A. 150:209, 1952.Crossref 2. Cohen, R. C.: Cough Fracture of Ribs , Brit. M. J. 1:133, 1949.Crossref 3. de Sèze, S.; Hubault, A., and Renier, J. C.: Fractures spontanées sous cortisone , Rev. rhumat., Paris 20:193, 1953. 4. Durand, P.: Le osteoporosi nel decoroso delle meningiti tubercolari trattate con streptomicina: studio sul metabolismo del calcio , Minerva pediat. 3:538, 1951. 5. Choremis, C.; Zervos, N.; Pantazis, S.; Priftis, N., and Papatheodorou, N.: Further Observations on the Application of Streptomycin in the Treatment of Tuberculous Meningitis in the Athens University Pediatric Clinic (Children's Hospital "Saint Sophia") , Acta. tuberc. scandinav. 25:8, 1950. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Journal of Diseases of Children American Medical Association

Spontaneous Fractures in Tuberculous Meningitis

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0096-6916
DOI
10.1001/archpedi.1957.04030020019004
Publisher site
See Article on Publisher Site

Abstract

Abstract Spontaneous fractures of the sternum have been described in adult patients with tuberculosis.1 No evidence of intrinsic bone disease has been found and no disturbance of calcium or phosphorus metabolism was noted in these cases. Furthermore, the apparent high incidence of rib fractures in tuberculous patients2 raises the question of an effect of the infection on bony structures. However, up to now patients with tuberculosis are not considered particularly liable to decalcification, except insofar as unusually prolonged bed rest may lead to demineralization. The scope of this paper is to report on four patients, all of them infants, who during their treatment for tuberculous meningitis developed spontaneous fractures of the lower extremities without any evidence of localized tuberculous lesions on the areas of the fractures. We do not consider the factor of bed rest alone as constituting a satisfactory explanation for these fractures. Report of Cases Case 1.—A References 1. Bass, H. E., and Small, M. J.: Spontaneous Fracture of Sternum in Tuberculosis , J. A. M. A. 150:209, 1952.Crossref 2. Cohen, R. C.: Cough Fracture of Ribs , Brit. M. J. 1:133, 1949.Crossref 3. de Sèze, S.; Hubault, A., and Renier, J. C.: Fractures spontanées sous cortisone , Rev. rhumat., Paris 20:193, 1953. 4. Durand, P.: Le osteoporosi nel decoroso delle meningiti tubercolari trattate con streptomicina: studio sul metabolismo del calcio , Minerva pediat. 3:538, 1951. 5. Choremis, C.; Zervos, N.; Pantazis, S.; Priftis, N., and Papatheodorou, N.: Further Observations on the Application of Streptomycin in the Treatment of Tuberculous Meningitis in the Athens University Pediatric Clinic (Children's Hospital "Saint Sophia") , Acta. tuberc. scandinav. 25:8, 1950.

Journal

A.M.A. Journal of Diseases of Children – American Medical Association

Published: Jul 1, 1957

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