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SOME RESULTS OF PATCH TESTS: A COMPILATION AND DISCUSSION OF CUTANEOUS REACTIONS TO ABOUT FIVE HUNDRED DIFFERENT SUBSTANCES, AS ELICITED BY OVER TEN THOUSAND TESTS IN APPROXIMATELY ONE THOUSAND PATIENTS

SOME RESULTS OF PATCH TESTS: A COMPILATION AND DISCUSSION OF CUTANEOUS REACTIONS TO ABOUT FIVE... Abstract This paper presents a compilation of the results of patch tests made on 998 persons, who were subjected to a total of 10,198 patch tests with about 500 different substances. Before considering the results obtained, we believe it essential to discuss briefly the nature of the dermatologic material and the circumstances under which these tests were performed. It must first be emphasized that we shall not attempt to consider the merits of patch tests as a diagnostic measure; nor shall we enter into a discussion of the technic of their application, of the reading of results or of the indications for patch tests in general.1 In agreement with the majority of observers, we are convinced of the value of patch tests as an aid to diagnosis, provided proper regard is given to their inherent limitations. Furthermore, it must be stated at the outset that this is not a report References 1. Sulzberger, Marion B., and Wise, Fred: The Contact or Patch Test: Its Uses, Advantages, and Limitations , Arch. Dermat. & Syph. 23:519 ( (March) ) 1931. 2. Sulzberger, Marion B., and Rostenberg, Adolph, Jr.: Practical Procedures in the Investigation of Certain Allergic Dermatoses , J. Allergy 6:448, 1935. 3. We are not here considering the high incidence of positive reactions to patch tests observed in the group representing dermatitis exfoliativa and erythroderma since we have figures on only 9 cases in that group; and since this seems to be a new and not previously recorded observation no valid conclusions can be drawn from the results in this small group. 4. Bloch, B., and Jaeger, cited by Darier, J.: Etiologie et pathogénie de l'eczème , Zentralbl. f. Haut- u. Geschlechtskr. 37:657, 1931. 5. Bloch, B.: Pathogenese des Ekzems , Arch. f. Dermat. u. Syph. 145:34, 1934. 6. A question mark after a diagnosis means that the diagnosis was doubtful. The diagnoses in all cases were taken from the patients' charts and not made by us personally. 7. (a) Osborne, E. D.; Putnam, E. D., and Saunders: Arch. Dermat. & Syph. , to be published; 8. cited by Stokes, J. H., and Garner, V. C.: Some Current Conceptions of Cutaneous Allergic Manifestations , Am. J. M. Sc. 191:566, 1936. 9. In our material, the mycotic ids form a possible exception. But, as we have pointed out in table 1, not all the cases listed under that diagnosis were proved examples of that condition, and even in the cases in which the diagnosis was proved, there was frequently another dermatosis besides a mycotic id. Accordingly, these facts tend to invalidate the statistical results so far as they appertain to dermatophytids. 10. Sulzberger, M. B.; Spain, W. C.; Sammis, F., and Shahon, H. I.: Studies in Hypersensitiveness in Certain Dermatoses: Neurodermatitis (Disseminated Type) , J. Allergy 3:423, 1932. 11. Stauffer, H.: Die Ekzem Proben , Arch. f. Dermat. u. Syph. 162:157, 1931. 12. Burckhardt, W.: Beiträge zur Ekzemfrage: Die Rolle des Alkali in der Pathogenese des Ekzems speziell des Gewerbeekzems , Arch. f. Dermat. u. Syph. 173:155, 1935. 13. Steiner, K.: Ueber die Ergebnisse und den Wert der "funktionellen Haut-prüfung" mittels der Läppchenprobe bei Hautkranken und bei Haut- "Gesunden," Arch. f. Dermat. u. Syph. 157:600, 1929. 14. Sulzberger, Marion B., and Hill, L. W.: Evolution of Atopic Dermatitis , Arch. Dermat. & Syph. 32:451 ( (Sept.) ) 1935. 15. (a) Peck, S. M., and Salomon, G.: Eczema of Infancy and Childhood , Am. J. Dis. Child. 46:1308 ( (Dec.) ) 1933. 16. (b) Peck, S. M.: Eczema of Infancy and Childhood: Neurodermatitis Disseminata and Atopy in Infancy , New York State J. Med. 34:957 ( (Nov. 15) ) 1934. 17. Percival, G. H.: Quantitative Observations on the Eczema Reaction , Brit. J. Dermat. 45:49, 1933. 18. R. L. Mayer ( Das Gewerbe Ekzem , Berlin, Julius Springer, 1931). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

SOME RESULTS OF PATCH TESTS: A COMPILATION AND DISCUSSION OF CUTANEOUS REACTIONS TO ABOUT FIVE HUNDRED DIFFERENT SUBSTANCES, AS ELICITED BY OVER TEN THOUSAND TESTS IN APPROXIMATELY ONE THOUSAND PATIENTS

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Publisher
American Medical Association
Copyright
Copyright © 1937 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1937.01470210059006
Publisher site
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Abstract

Abstract This paper presents a compilation of the results of patch tests made on 998 persons, who were subjected to a total of 10,198 patch tests with about 500 different substances. Before considering the results obtained, we believe it essential to discuss briefly the nature of the dermatologic material and the circumstances under which these tests were performed. It must first be emphasized that we shall not attempt to consider the merits of patch tests as a diagnostic measure; nor shall we enter into a discussion of the technic of their application, of the reading of results or of the indications for patch tests in general.1 In agreement with the majority of observers, we are convinced of the value of patch tests as an aid to diagnosis, provided proper regard is given to their inherent limitations. Furthermore, it must be stated at the outset that this is not a report References 1. Sulzberger, Marion B., and Wise, Fred: The Contact or Patch Test: Its Uses, Advantages, and Limitations , Arch. Dermat. & Syph. 23:519 ( (March) ) 1931. 2. Sulzberger, Marion B., and Rostenberg, Adolph, Jr.: Practical Procedures in the Investigation of Certain Allergic Dermatoses , J. Allergy 6:448, 1935. 3. We are not here considering the high incidence of positive reactions to patch tests observed in the group representing dermatitis exfoliativa and erythroderma since we have figures on only 9 cases in that group; and since this seems to be a new and not previously recorded observation no valid conclusions can be drawn from the results in this small group. 4. Bloch, B., and Jaeger, cited by Darier, J.: Etiologie et pathogénie de l'eczème , Zentralbl. f. Haut- u. Geschlechtskr. 37:657, 1931. 5. Bloch, B.: Pathogenese des Ekzems , Arch. f. Dermat. u. Syph. 145:34, 1934. 6. A question mark after a diagnosis means that the diagnosis was doubtful. The diagnoses in all cases were taken from the patients' charts and not made by us personally. 7. (a) Osborne, E. D.; Putnam, E. D., and Saunders: Arch. Dermat. & Syph. , to be published; 8. cited by Stokes, J. H., and Garner, V. C.: Some Current Conceptions of Cutaneous Allergic Manifestations , Am. J. M. Sc. 191:566, 1936. 9. In our material, the mycotic ids form a possible exception. But, as we have pointed out in table 1, not all the cases listed under that diagnosis were proved examples of that condition, and even in the cases in which the diagnosis was proved, there was frequently another dermatosis besides a mycotic id. Accordingly, these facts tend to invalidate the statistical results so far as they appertain to dermatophytids. 10. Sulzberger, M. B.; Spain, W. C.; Sammis, F., and Shahon, H. I.: Studies in Hypersensitiveness in Certain Dermatoses: Neurodermatitis (Disseminated Type) , J. Allergy 3:423, 1932. 11. Stauffer, H.: Die Ekzem Proben , Arch. f. Dermat. u. Syph. 162:157, 1931. 12. Burckhardt, W.: Beiträge zur Ekzemfrage: Die Rolle des Alkali in der Pathogenese des Ekzems speziell des Gewerbeekzems , Arch. f. Dermat. u. Syph. 173:155, 1935. 13. Steiner, K.: Ueber die Ergebnisse und den Wert der "funktionellen Haut-prüfung" mittels der Läppchenprobe bei Hautkranken und bei Haut- "Gesunden," Arch. f. Dermat. u. Syph. 157:600, 1929. 14. Sulzberger, Marion B., and Hill, L. W.: Evolution of Atopic Dermatitis , Arch. Dermat. & Syph. 32:451 ( (Sept.) ) 1935. 15. (a) Peck, S. M., and Salomon, G.: Eczema of Infancy and Childhood , Am. J. Dis. Child. 46:1308 ( (Dec.) ) 1933. 16. (b) Peck, S. M.: Eczema of Infancy and Childhood: Neurodermatitis Disseminata and Atopy in Infancy , New York State J. Med. 34:957 ( (Nov. 15) ) 1934. 17. Percival, G. H.: Quantitative Observations on the Eczema Reaction , Brit. J. Dermat. 45:49, 1933. 18. R. L. Mayer ( Das Gewerbe Ekzem , Berlin, Julius Springer, 1931).

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Mar 1, 1937

References