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Solitary Intracranial Metastasis by Hodgkin's Disease

Solitary Intracranial Metastasis by Hodgkin's Disease Abstract INVASION of the intracranial cavity by Hodgkin's granuloma is considered unusual and a solitary metastasis rare. Such a case is presented. Report of a Case A 38-year-old white right-handed female teacher, was hospitalized in March 1965 after a five or six month history of dry cough, low grade fever (100 F [37.8 C] orally), malaise, easy fatigability, and generalized pruritis. The medical history was unremarkable. A chest x-ray film by her family physician revealed a 6 × 8-cm superior mediastinal mass (Fig 1).Physical examination revealed a well-developed, well-nourished woman with an oral temperature of 100 F. A blood pressure differential of 110/90 mm Hg in the left arm, 70/60 mm Hg in the right arm, was recorded. A mild dilatation of the venous pattern over the upper anterior portion of the chest wall was also seen. Otherwise the physical examination was within normal limits.Laboratory data revealed a hemoglobin References 1. Russell, D.S., and Rubinstein, L.J.: Pathology of Tumors of the Nervous System , ed 1, London: E. Arnold, 1959. 2. Jackson, H., Jr., and Parker, F., Jr.: Hodgkin's Disease and Allied Disorders , New York: Oxford University Press, 1957. 3. John, H.T., and Nabarro, J.D.N.: Intracranial Manifestations of Malignant Lymphoma , Brit J Cancer 9:386-400, 1955.Crossref 4. Williams, H.M., et al: Neurological Complications of Lymphomas and Leukemias , Springfield, Ill: Charles C Thomas, Publisher, 1959. 5. Sparling, H.J.; Adams, R.D.; and Parker, F., Jr.: Involvement of the Nervous System by Malignant Lymphoma , Medicine 26:285-332, 1947.Crossref 6. Hutchinson, E.C., et al: Neurological Complications of the Reticuloses , Brain 81:75-92, 1958.Crossref 7. Fein, S.B., and Nevill, V.A.: Cerebral Hodgkin's Disease: Case Report of Hodgkin's Granuloma With Cerebral Invasion , Amer J Med 17:291-294, 1954.Crossref 8. Schricker, J.L., Jr., and Smith, D.E.: Primary Intracerebral Hodgkin's Disease , Cancer 8:629-633, 1955.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Solitary Intracranial Metastasis by Hodgkin's Disease

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Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1967.00300050096017
Publisher site
See Article on Publisher Site

Abstract

Abstract INVASION of the intracranial cavity by Hodgkin's granuloma is considered unusual and a solitary metastasis rare. Such a case is presented. Report of a Case A 38-year-old white right-handed female teacher, was hospitalized in March 1965 after a five or six month history of dry cough, low grade fever (100 F [37.8 C] orally), malaise, easy fatigability, and generalized pruritis. The medical history was unremarkable. A chest x-ray film by her family physician revealed a 6 × 8-cm superior mediastinal mass (Fig 1).Physical examination revealed a well-developed, well-nourished woman with an oral temperature of 100 F. A blood pressure differential of 110/90 mm Hg in the left arm, 70/60 mm Hg in the right arm, was recorded. A mild dilatation of the venous pattern over the upper anterior portion of the chest wall was also seen. Otherwise the physical examination was within normal limits.Laboratory data revealed a hemoglobin References 1. Russell, D.S., and Rubinstein, L.J.: Pathology of Tumors of the Nervous System , ed 1, London: E. Arnold, 1959. 2. Jackson, H., Jr., and Parker, F., Jr.: Hodgkin's Disease and Allied Disorders , New York: Oxford University Press, 1957. 3. John, H.T., and Nabarro, J.D.N.: Intracranial Manifestations of Malignant Lymphoma , Brit J Cancer 9:386-400, 1955.Crossref 4. Williams, H.M., et al: Neurological Complications of Lymphomas and Leukemias , Springfield, Ill: Charles C Thomas, Publisher, 1959. 5. Sparling, H.J.; Adams, R.D.; and Parker, F., Jr.: Involvement of the Nervous System by Malignant Lymphoma , Medicine 26:285-332, 1947.Crossref 6. Hutchinson, E.C., et al: Neurological Complications of the Reticuloses , Brain 81:75-92, 1958.Crossref 7. Fein, S.B., and Nevill, V.A.: Cerebral Hodgkin's Disease: Case Report of Hodgkin's Granuloma With Cerebral Invasion , Amer J Med 17:291-294, 1954.Crossref 8. Schricker, J.L., Jr., and Smith, D.E.: Primary Intracerebral Hodgkin's Disease , Cancer 8:629-633, 1955.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Dec 1, 1967

References