Abstract Calcification of soft tissues is known to occur frequently in progressive systemic sclerosis (PSS) and dermatomyositis. To our knowledge, only seven case reports have appeared concerning this abnormality in systemic lupus erythematosus (SLE). We describe four patients with well-documented SLE who developed calcification in subcutaneous tissue, muscle, or periarticular structures. The pattern and localization of the calcification can mimic those seen in other disorders. References 1. Kabir DI, Malkinson FD: Lupus erythematosus and calcinosis cutis . Arch Dermatol 100:17-22, 1969.Crossref 2. Keats TE: The collagen diseases: A demonstration of the nonspecificity of their extrapulmonary manifestations . Am J Roentgenol Radium Ther Nucl Med 86:938-943, 1961. 3. Savin JA: SLE with ectopic calcification . Br J Dermatol 84:191-192, 1971. 4. Coltoiu AL, Mateescu D, Diaconu J: SLE, calcifying polymyositis and ascitogenic cirrhosis . Rom Med Rev 12:29-32, 1968. 5. Tay CH: Cutaneous manifestations of systemic lupus erythematosus: A clinical study from Singapore . Australas J Dermatol 11:30-41, 1970.Crossref 6. Powell RJ: Systemic lupus erythematosus with widespread subcutaneous fat calcification . Proc R Soc Med 67:215-217, 1974. 7. Dubois EL, Chandor S, Friou GJ, et al: Progressive systemic sclerosis (PSS) and localized scleroderma (Morphea) with positive LE cell test and unusual systemic manifestations compatible with systemic lupus erythematosus . Medicine 50:199-222, 1971.Crossref 8. Cohen AS, Reynolds WE, Franklin EC, et al: Preliminary criteria for the classification of systemic lupus erythematosus . Bull Rheum Dis 21:643-648, 1971. 9. Muller SA, Winkelmann RK, Brunsting LA: Calcinosis in dermatomyositis . Arch Dermatol 79:669-673, 1959.Crossref 10. Muller SA, Brunsting LA, Winkelmann RK: Calcinosis cutis: Its relationship to scleroderma . Arch Dermatol 80:15-21, 1959.Crossref 11. Dubois EL: Clinical picture of SLE , in Dubois EL (ed): Lupus Erythematosus: A Review of the Current Status of Discoid and Systemic Lupus Erythematosus and Their Variants , ed 2. Los Angeles, University of Southern California Press, 1974, pp 232-279. 12. White W: Lupus erythematosus and polymyositis . Proc R Soc Med 52:1035-1037, 1959. 13. Shawker TH, Dennis JM: Periarticular calcifications in pyogenic arthritis . Am J Roentgenol Radium Ther Nucl Med 113:650-654, 1971.Crossref
Archives of Dermatology – American Medical Association
Published: Mar 1, 1975
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