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Smooth-Muscle Tumors of the Skin

Smooth-Muscle Tumors of the Skin Abstract Smooth-muscle tumors of the skin occur infrequently. We wish to report a series of 33 cases in which such lesions were present. This group is divided into 23 cases of leiomyoma cutis; 8 cases of angiomyoma; 1 case of nodular, or so-called dartoic, myoma, and 1 case of leiomyosarcoma. The occurrence of only one example of nodular, or dartoic, myoma in this series can be explained on the basis that such tumors arise from special rows of smooth-muscle cells in the scrotum, nipple, and external genitalia deep in the subcutaneous tissue and, therefore, are seen primarily by the surgeon for excision. We have been especially interested in this study in regard to why some myomas are painful and some are not. Particular attention was given to use of histochemical techniques to differentiate myomatous tissue from other mesodermal tissues. Survey of Literature It is not our purpose References 1. Ormsby, O. S.: Leiomyoma Cutis , Arch. Dermat. & Syph. 11:466-480 ( (April) ) 1925. 2. Besnier, E.: Les dermatomyomes (fibromyomes, liomyomes, ou myomes cutanes) , Ann. dermat. et syph. 1:25-43, 1880. 3. Kaposi, M.: Lecons sur les maladies de la peau , translated by E. Besnier and A. Doyon, Paris, G. Masson, 1881, Vol. 2, p. 346. 4. Dictel, F., in J. Jadassohn: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Springer-Verlag, 1932, Vol. 12. 5. Stout, A. P.: Solitary Cutaneous and Subcutaneous Leiomyoma , Am. J. Cancer 29:435-469 ( (March) ) 1937. 6. Stout, A. P.: Sarcomas of Soft Parts , J. Missouri M. A. 44:329-334 ( (May) ) 1947. 7. Stout, A. P.: Tumors of the Soft Tissues, in Atlas of Tumor Pathology , National Research Council, Armed Forces Institute of Pathology, 1953, Section II, Fascicle (5) , p. 38. 8. Jansen, L. H.: Leiomyomata cutis , Acta dermat.-venereol. 32:40-50, 1952. 9. Saunders, T. S., and Fitzpatrick, T. B.: Cutaneous Leiomyoma: Classification and Report of Solitary Angioleiomyoma , A. M. A. Arch. Dermat. 74:389-392 ( (Oct.) ) 1956. 10. Vilanova, X., and Grau Barbera, L.: Contribucion al conocimiento de los tumores glomicos: Forma angioleiomuscular (2° caso) , Acta dermosif. 35:568-571 ( (March) ) 1944. 11. Abulafia, J., and Grinspan, D.: Leiomiomas de la piel, con especial referencia a las formas solitarias; Ensayo de classificación anátomoclínica e histogenetica , Arch. argent. dermat. 6:1-46 ( (March) ) 1956. 12. Nödl, F.: Multiple Leiomyome der Haut, ein neurocutanes Syndrom , Hautarzt 4:365-371 ( (Aug.) ) 1953. 13. Grzybowski, M.: Contribution à l'étude de l'histologie des myomes cutanés , Ann. dermat. et. syph. 4:852-860 ( (Sept.) ) 1933. 14. Radermecker, J., and van Bogaert, L.: Sur la leiomyomatose douloureuse à disposition systematisée naévique (Contribution à l'étude des dysplasies mésodermiques congénitales) , Dermatologica 83:201-214, 1941. 15. Sonck, C. E.: Myomatosis Cutis Miliaris: Report of a Case , Acta dermat.-venereol. 31:297-303, 1951. 16. Levack, J., and Dick, A.: Cutaneous Leiomyosarcoma with Lymphatic Spread: A Report of 2 Cases , Glasgow M. J. 36:337-342 ( (Oct.) ) 1955. 17. Ackerman, L. V., and Stout, A. P.: Leiomyosarcoma of Arm , J. Missouri M. A. 44:592-593 ( (Aug.) ) 1947. 18. Dubuisson, M.: Muscular Contraction , edited by W. Bladergroen, Springfield, Ill., Charles C Thomas, Publisher, 1954. 19. Ashmarin, I. P.: Investigation on the Properties of Contractile Muscle Proteins by New Methods , Chem. Abstr. 45:9101, 1951. 20. Barrnett, R. J., and Seligman, A. M.: Histochemical Demonstration of Protein-Bound Sulfhydryl Groups , Science 116:323-327 ( (Sept. 26) ) 1952. 21. Fishman, W. H., and Baker, J. R.: Cellular Localization of β-Glucuronidase in Rat Tissues , J. Histochem. 4:570-587 ( (Nov.) ) 1956. 22. Winkelmann, R. K., and Schmit, R. W.: A Simple Silver Method for Nerve Axoplasm , Proc. Staff Meet. Mayo Clin. 32:217-222 ( (May 1) ) 1957. 23. Winkelmann, R. K., and Schmit, R. W.: Factors Related to the Staining of Nerve Axoplasm with Concentrated Silver Solutions , Proc. Staff Meet. Mayo Clin. 32:222-226 ( (May 1) ) 1957. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1959.01560130034004
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Abstract

Abstract Smooth-muscle tumors of the skin occur infrequently. We wish to report a series of 33 cases in which such lesions were present. This group is divided into 23 cases of leiomyoma cutis; 8 cases of angiomyoma; 1 case of nodular, or so-called dartoic, myoma, and 1 case of leiomyosarcoma. The occurrence of only one example of nodular, or dartoic, myoma in this series can be explained on the basis that such tumors arise from special rows of smooth-muscle cells in the scrotum, nipple, and external genitalia deep in the subcutaneous tissue and, therefore, are seen primarily by the surgeon for excision. We have been especially interested in this study in regard to why some myomas are painful and some are not. Particular attention was given to use of histochemical techniques to differentiate myomatous tissue from other mesodermal tissues. Survey of Literature It is not our purpose References 1. Ormsby, O. S.: Leiomyoma Cutis , Arch. Dermat. & Syph. 11:466-480 ( (April) ) 1925. 2. Besnier, E.: Les dermatomyomes (fibromyomes, liomyomes, ou myomes cutanes) , Ann. dermat. et syph. 1:25-43, 1880. 3. Kaposi, M.: Lecons sur les maladies de la peau , translated by E. Besnier and A. Doyon, Paris, G. Masson, 1881, Vol. 2, p. 346. 4. Dictel, F., in J. Jadassohn: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Springer-Verlag, 1932, Vol. 12. 5. Stout, A. P.: Solitary Cutaneous and Subcutaneous Leiomyoma , Am. J. Cancer 29:435-469 ( (March) ) 1937. 6. Stout, A. P.: Sarcomas of Soft Parts , J. Missouri M. A. 44:329-334 ( (May) ) 1947. 7. Stout, A. P.: Tumors of the Soft Tissues, in Atlas of Tumor Pathology , National Research Council, Armed Forces Institute of Pathology, 1953, Section II, Fascicle (5) , p. 38. 8. Jansen, L. H.: Leiomyomata cutis , Acta dermat.-venereol. 32:40-50, 1952. 9. Saunders, T. S., and Fitzpatrick, T. B.: Cutaneous Leiomyoma: Classification and Report of Solitary Angioleiomyoma , A. M. A. Arch. Dermat. 74:389-392 ( (Oct.) ) 1956. 10. Vilanova, X., and Grau Barbera, L.: Contribucion al conocimiento de los tumores glomicos: Forma angioleiomuscular (2° caso) , Acta dermosif. 35:568-571 ( (March) ) 1944. 11. Abulafia, J., and Grinspan, D.: Leiomiomas de la piel, con especial referencia a las formas solitarias; Ensayo de classificación anátomoclínica e histogenetica , Arch. argent. dermat. 6:1-46 ( (March) ) 1956. 12. Nödl, F.: Multiple Leiomyome der Haut, ein neurocutanes Syndrom , Hautarzt 4:365-371 ( (Aug.) ) 1953. 13. Grzybowski, M.: Contribution à l'étude de l'histologie des myomes cutanés , Ann. dermat. et. syph. 4:852-860 ( (Sept.) ) 1933. 14. Radermecker, J., and van Bogaert, L.: Sur la leiomyomatose douloureuse à disposition systematisée naévique (Contribution à l'étude des dysplasies mésodermiques congénitales) , Dermatologica 83:201-214, 1941. 15. Sonck, C. E.: Myomatosis Cutis Miliaris: Report of a Case , Acta dermat.-venereol. 31:297-303, 1951. 16. Levack, J., and Dick, A.: Cutaneous Leiomyosarcoma with Lymphatic Spread: A Report of 2 Cases , Glasgow M. J. 36:337-342 ( (Oct.) ) 1955. 17. Ackerman, L. V., and Stout, A. P.: Leiomyosarcoma of Arm , J. Missouri M. A. 44:592-593 ( (Aug.) ) 1947. 18. Dubuisson, M.: Muscular Contraction , edited by W. Bladergroen, Springfield, Ill., Charles C Thomas, Publisher, 1954. 19. Ashmarin, I. P.: Investigation on the Properties of Contractile Muscle Proteins by New Methods , Chem. Abstr. 45:9101, 1951. 20. Barrnett, R. J., and Seligman, A. M.: Histochemical Demonstration of Protein-Bound Sulfhydryl Groups , Science 116:323-327 ( (Sept. 26) ) 1952. 21. Fishman, W. H., and Baker, J. R.: Cellular Localization of β-Glucuronidase in Rat Tissues , J. Histochem. 4:570-587 ( (Nov.) ) 1956. 22. Winkelmann, R. K., and Schmit, R. W.: A Simple Silver Method for Nerve Axoplasm , Proc. Staff Meet. Mayo Clin. 32:217-222 ( (May 1) ) 1957. 23. Winkelmann, R. K., and Schmit, R. W.: Factors Related to the Staining of Nerve Axoplasm with Concentrated Silver Solutions , Proc. Staff Meet. Mayo Clin. 32:222-226 ( (May 1) ) 1957.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Jan 1, 1959

References