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Sjögren's Syndrome and Late-Life Myopathy

Sjögren's Syndrome and Late-Life Myopathy Abstract IN 1933 Henrik Sjögren1 described a syndrome consisting of the triad of keratoconjunctivitis sicca ("dry eyes"), xerostomia ("dry mouth"), and rheumatoid arthritis. Lacrimal or salivary gland enlargement may or may not be present. Two of the three major components are generally considered sufficient for the diagnosis.2 In 1962 Silberberg and Drachman3 reported four cases of late-life myopathy occurring with Sjögren's syndrome. Although one of their patients had a history of arthritic symptoms, examination of that patient disclosed no significant abnormalities of the joints. This report describes a patient who presented with late-life myopathy and was found to have Sjögren's syndrome, including active rheumatoid arthritis. She is thought to represent the first published report of a patient with Sjögren's syndrome who demonstrated both active rheumatoid arthritis and active myopathy. Report of a Case A 45-year-old Negro housewife was first admitted to the hospital in 1960 because of References 1. Sjögren, H.: Zur Kenntnis der Keratoconjunctivitis sicca (Keratitis filiformis bei hypofunktion der Tranendrusen) , Acta Opthal 11:1, 1933. 2. Bloch, K.J., et al: Sjögren's Syndrome: A Clinical, Pathological, and Serological Study of 62 Cases , Medicine 44:187-231, 1965.Crossref 3. Silberberg, D.H., and Drachman, D.D.: Late-Life Myopathy Occurring With Sjögren's Syndrome , Arch Neurol 6:428-438, 1962.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Sjögren's Syndrome and Late-Life Myopathy

FOX, J. THOMAS
Archives of Neurology , Volume 15 (4) – Oct 1, 1966
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Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1966.00470160063008
Publisher site
See Article on Publisher Site

Abstract

Abstract IN 1933 Henrik Sjögren1 described a syndrome consisting of the triad of keratoconjunctivitis sicca ("dry eyes"), xerostomia ("dry mouth"), and rheumatoid arthritis. Lacrimal or salivary gland enlargement may or may not be present. Two of the three major components are generally considered sufficient for the diagnosis.2 In 1962 Silberberg and Drachman3 reported four cases of late-life myopathy occurring with Sjögren's syndrome. Although one of their patients had a history of arthritic symptoms, examination of that patient disclosed no significant abnormalities of the joints. This report describes a patient who presented with late-life myopathy and was found to have Sjögren's syndrome, including active rheumatoid arthritis. She is thought to represent the first published report of a patient with Sjögren's syndrome who demonstrated both active rheumatoid arthritis and active myopathy. Report of a Case A 45-year-old Negro housewife was first admitted to the hospital in 1960 because of References 1. Sjögren, H.: Zur Kenntnis der Keratoconjunctivitis sicca (Keratitis filiformis bei hypofunktion der Tranendrusen) , Acta Opthal 11:1, 1933. 2. Bloch, K.J., et al: Sjögren's Syndrome: A Clinical, Pathological, and Serological Study of 62 Cases , Medicine 44:187-231, 1965.Crossref 3. Silberberg, D.H., and Drachman, D.D.: Late-Life Myopathy Occurring With Sjögren's Syndrome , Arch Neurol 6:428-438, 1962.Crossref

Journal

Archives of Neurology – American Medical Association

Published: Oct 1, 1966

References

  • Zur Kenntnis der Keratoconjunctivitis sicca (Keratitis filiformis bei hypofunktion der Tranendrusen)
    Sjögren , H.
  • Sjögren's Syndrome: A Clinical, Pathological, and Serological Study of 62 Cases
    Bloch , K.J., et al
  • Late-Life Myopathy Occurring With Sjögren's Syndrome
    Silberberg , D.H., and Drachman, D.D.