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Single vs Multiple Embryo Transfer

Single vs Multiple Embryo Transfer Editorial Opinion Comparative Costs and a Call for Change Pooja Mehta, MD; Mark Pauly, PhD The equivalent efficacy and superior safety of elective single tient costs could have been avoided if twins and higher-order embryo transfer (SET) compared with elective multiple em- multiples conceived with assisted reproduction had been born bryo transfer (MET) after in vitro fertilization (IVF) has been as singletons. established in recent medi- The study’s greatest strength was that it achieved long- cal literature. The transfer of term follow-up of a large population of 233 850 infants born Related article page 1045 a single high-quality embryo over a 10-year period. A 100% linkage rate between the birth selected from a larger num- registry and the reproductive technology registry is reported, ber of available embryos after IVF does not decrease implan- creating a rich source of data when combined with childhood tation rates compared with MET and decreases the rate of twins hospital use records. However, the study likely underesti- from 30% to between 1% and 2%. mated the costs attributable to assisted reproductive technol- To reduce the complications associated with twin and ogy because outpatient costs are not accounted for. higher-order multiple births—including medical and deliv- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Single vs Multiple Embryo Transfer

JAMA Pediatrics , Volume 168 (11) – Nov 1, 2014

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Publisher
American Medical Association
Copyright
Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2014.1683
pmid
25222350
Publisher site
See Article on Publisher Site

Abstract

Editorial Opinion Comparative Costs and a Call for Change Pooja Mehta, MD; Mark Pauly, PhD The equivalent efficacy and superior safety of elective single tient costs could have been avoided if twins and higher-order embryo transfer (SET) compared with elective multiple em- multiples conceived with assisted reproduction had been born bryo transfer (MET) after in vitro fertilization (IVF) has been as singletons. established in recent medi- The study’s greatest strength was that it achieved long- cal literature. The transfer of term follow-up of a large population of 233 850 infants born Related article page 1045 a single high-quality embryo over a 10-year period. A 100% linkage rate between the birth selected from a larger num- registry and the reproductive technology registry is reported, ber of available embryos after IVF does not decrease implan- creating a rich source of data when combined with childhood tation rates compared with MET and decreases the rate of twins hospital use records. However, the study likely underesti- from 30% to between 1% and 2%. mated the costs attributable to assisted reproductive technol- To reduce the complications associated with twin and ogy because outpatient costs are not accounted for. higher-order multiple births—including medical and deliv-

Journal

JAMA PediatricsAmerican Medical Association

Published: Nov 1, 2014

References