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Simplification of the Revised Geneva Score for Assessing Clinical Probability of Pulmonary Embolism

Simplification of the Revised Geneva Score for Assessing Clinical Probability of Pulmonary Embolism ORIGINAL INVESTIGATION Simplification of the Revised Geneva Score for Assessing Clinical Probability of Pulmonary Embolism Frederikus A. Klok, MD; Inge C. M. Mos, MD; Mathilde Nijkeuter, MD, PhD; Marc Righini, MD, PhD; Arnaud Perrier, MD, PhD; Gre´goire Le Gal, MD, PhD; Menno V. Huisman, MD, PhD Background: The revised Geneva score is a fully stan- Results: The complete study population had an overall dardized clinical decision rule (CDR) in the diagnostic prevalence of venous thromboembolism of 23%. The di- workup of patients with suspected pulmonary embo- agnostic accuracy between the 2 CDRs did not differ (area lism (PE). The variables of the decision rule have differ- under the curve for the revised Geneva score was 0.75 ent weights, which could lead to miscalculations in an [95% confidence interval, 0.71-0.78] vs 0.74 [0.70- acute setting. We have validated a simplified version of 0.77] for the simplified revised Geneva score). During the revised Geneva score. 3 months of follow-up, no patient with a combination of either a low (0%; 95% confidence interval, 0.0%- Methods: Data from 1049 patients from 2 large prospec- 1.7%) or intermediate (0%; 0.0%-2.8%) clinical prob- tive diagnostic trials that included patients with sus- ability, or a “PE http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Simplification of the Revised Geneva Score for Assessing Clinical Probability of Pulmonary Embolism

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References (21)

Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinte.168.19.2131
pmid
18955643
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Simplification of the Revised Geneva Score for Assessing Clinical Probability of Pulmonary Embolism Frederikus A. Klok, MD; Inge C. M. Mos, MD; Mathilde Nijkeuter, MD, PhD; Marc Righini, MD, PhD; Arnaud Perrier, MD, PhD; Gre´goire Le Gal, MD, PhD; Menno V. Huisman, MD, PhD Background: The revised Geneva score is a fully stan- Results: The complete study population had an overall dardized clinical decision rule (CDR) in the diagnostic prevalence of venous thromboembolism of 23%. The di- workup of patients with suspected pulmonary embo- agnostic accuracy between the 2 CDRs did not differ (area lism (PE). The variables of the decision rule have differ- under the curve for the revised Geneva score was 0.75 ent weights, which could lead to miscalculations in an [95% confidence interval, 0.71-0.78] vs 0.74 [0.70- acute setting. We have validated a simplified version of 0.77] for the simplified revised Geneva score). During the revised Geneva score. 3 months of follow-up, no patient with a combination of either a low (0%; 95% confidence interval, 0.0%- Methods: Data from 1049 patients from 2 large prospec- 1.7%) or intermediate (0%; 0.0%-2.8%) clinical prob- tive diagnostic trials that included patients with sus- ability, or a “PE

Journal

JAMA Internal Medicine – American Medical Association

Published: Oct 27, 2008

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