Sickle Cell Screening
Abstract
To the Editor.—
We are gratified that Uddin et al (227:1405, 1974) have found the automated dithionite test (Clin Chem 17:1033, 1971) so reliable in sickle cell hemoglobin screening.
Because of the closing caveat about screening civilian populations, emphasis on several points is offered.
The use of the automated dithionite test (ADT) as the initial method of screening, and the reservation of hemoglobin electrophoresis (HE) for those cases that are ADT-positive or that require genetic...