Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Sickle Cell Anemia: Report of Two Cases in Children, With Necropsy in One Case

Sickle Cell Anemia: Report of Two Cases in Children, With Necropsy in One Case Abstract J. B. Herrick,1 in 1910, reported a peculiar dyscrasia characterized by severe anemia, with the occurrence in the blood of elongated and sickle-shaped erythrocytes. Three instances of this condition have since been described, one by R. E. Washburn;2 one by Cook and Myer,3 and one by V. R. Mason.4 Emmel5 further studied the blood of Cook and Myer's case, demonstrating the existence of phagocytosis of the erythrocytes by large mononuclear leukocytes in the peripheral circulation. He also pointed out the fact that when sealed sterile preparations of the fresh blood were allowed to stand at room temperature for varying periods of time, many of the circular erythrocytes underwent transformation into elongated and sickle shapes similar to those seen in the freshly drawn blood. Furthermore, he showed that the blood of the patient's father, though normal to all appearances when drawn, underwent similar changes on standing. Guthrie http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Sickle Cell Anemia: Report of Two Cases in Children, With Necropsy in One Case

Loading next page...
 
/lp/american-medical-association/sickle-cell-anemia-report-of-two-cases-in-children-with-necropsy-in-Ix6NGt30sA
Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1987.04460060030025
Publisher site
See Article on Publisher Site

Abstract

Abstract J. B. Herrick,1 in 1910, reported a peculiar dyscrasia characterized by severe anemia, with the occurrence in the blood of elongated and sickle-shaped erythrocytes. Three instances of this condition have since been described, one by R. E. Washburn;2 one by Cook and Myer,3 and one by V. R. Mason.4 Emmel5 further studied the blood of Cook and Myer's case, demonstrating the existence of phagocytosis of the erythrocytes by large mononuclear leukocytes in the peripheral circulation. He also pointed out the fact that when sealed sterile preparations of the fresh blood were allowed to stand at room temperature for varying periods of time, many of the circular erythrocytes underwent transformation into elongated and sickle shapes similar to those seen in the freshly drawn blood. Furthermore, he showed that the blood of the patient's father, though normal to all appearances when drawn, underwent similar changes on standing. Guthrie

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jun 1, 1987

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month