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Severe Hypertrichosis of the External Ear Canal During Minoxidil Therapy

Severe Hypertrichosis of the External Ear Canal During Minoxidil Therapy Abstract • Minoxidil is a potent peripheral vasodilator used to treat patients with severe hypertension that is unresponsive to other medications. Hypertrichosis of the forehead, face, neck, shoulders, upper part of the arms, and legs is a frequent side effect that occurs in the majority of patients that use this drug. This phenomenon appears to be due to increased blood flow to hair follicles, with resultant excessive hair growth. We describe a patient with severe hypertrichosis of the external ear canal resulting in chronic otitis externa and hearing loss. (Arch Otolaryngol Head Neck Surg 1988;114:918-919) References 1. Dargie HJ, Dollery CT, Danial J: Minoxidil in resistant hypertension . Lancet 1977;2:515-518.Crossref 2. Linas SL, Nies AS: Minoxidil . Ann Intern Med 1981;94:61-65.Crossref 3. Jacomb RC, Brunnbery FJ: The use of minoxidil in the treatment of severe essential hypertension: A report on 100 patients . Clin Sci 1976;51:579-581. 4. Gilmore EG, Weil J, Chidsey C: Treatment of essential hypertension with a new vasodilator in combination with β-adrenergic blockade . N Engl J Med 1970;282:521-527.Crossref 5. Mitchell HC, Pettinger WA: Long-term treatment of refractory hypertensive patients with minoxidil . JAMA 1978;239:2131-2138.Crossref 6. Kuesch GW, Weidmann P, Campese V, et al: Minoxidil therapy in refractory hypertension: Analysis of 155 patients . Nephron 1978;21:1-15.Crossref 7. Sinaiko AR, O'Dea RF, Mirkin BL: Clinical response of hypertensive children to long-term minoxidil therapy . J Cardiovasc Pharmacol 1980; 2:181-188.Crossref 8. Earhart RN, Ball J, Nuss DD, et al: Minoxidil-induced hypertrichosis: Treatment with calcium thioglycolate depilatory . South Med J 1977;70:442-443.Crossref 9. Burton JL, Marshall A: Hypertrichosis due to minoxidil . Br J Dermatol 1979;101:593-595.Crossref 10. Wester RC, Maibach HI, Guy RH, et al: Minoxidil stimulates cutaneous blood flow in human balding scalps: Pharmacodynamics measured by laser Doppler velocimetry and photopulse plethysmography . J Invest Dermatol 1984; 82:515-517.Crossref 11. Vanderveen EE, Ellis CN, Kang S, et al: Topical minoxidil for hair regrowth . J Am Acad Dermatol 1984;11:416-421.Crossref 12. Olsen EA, Weiner MS, Delong ER, et al: Topical minoxidil in early male pattern baldness . J Am Acad Dermatol 1985;13:185-192.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology - Head & Neck Surgery American Medical Association

Severe Hypertrichosis of the External Ear Canal During Minoxidil Therapy

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Publisher
American Medical Association
Copyright
Copyright © 1988 American Medical Association. All Rights Reserved.
ISSN
0886-4470
eISSN
1538-361X
DOI
10.1001/archotol.1988.01860200102029
Publisher site
See Article on Publisher Site

Abstract

Abstract • Minoxidil is a potent peripheral vasodilator used to treat patients with severe hypertension that is unresponsive to other medications. Hypertrichosis of the forehead, face, neck, shoulders, upper part of the arms, and legs is a frequent side effect that occurs in the majority of patients that use this drug. This phenomenon appears to be due to increased blood flow to hair follicles, with resultant excessive hair growth. We describe a patient with severe hypertrichosis of the external ear canal resulting in chronic otitis externa and hearing loss. (Arch Otolaryngol Head Neck Surg 1988;114:918-919) References 1. Dargie HJ, Dollery CT, Danial J: Minoxidil in resistant hypertension . Lancet 1977;2:515-518.Crossref 2. Linas SL, Nies AS: Minoxidil . Ann Intern Med 1981;94:61-65.Crossref 3. Jacomb RC, Brunnbery FJ: The use of minoxidil in the treatment of severe essential hypertension: A report on 100 patients . Clin Sci 1976;51:579-581. 4. Gilmore EG, Weil J, Chidsey C: Treatment of essential hypertension with a new vasodilator in combination with β-adrenergic blockade . N Engl J Med 1970;282:521-527.Crossref 5. Mitchell HC, Pettinger WA: Long-term treatment of refractory hypertensive patients with minoxidil . JAMA 1978;239:2131-2138.Crossref 6. Kuesch GW, Weidmann P, Campese V, et al: Minoxidil therapy in refractory hypertension: Analysis of 155 patients . Nephron 1978;21:1-15.Crossref 7. Sinaiko AR, O'Dea RF, Mirkin BL: Clinical response of hypertensive children to long-term minoxidil therapy . J Cardiovasc Pharmacol 1980; 2:181-188.Crossref 8. Earhart RN, Ball J, Nuss DD, et al: Minoxidil-induced hypertrichosis: Treatment with calcium thioglycolate depilatory . South Med J 1977;70:442-443.Crossref 9. Burton JL, Marshall A: Hypertrichosis due to minoxidil . Br J Dermatol 1979;101:593-595.Crossref 10. Wester RC, Maibach HI, Guy RH, et al: Minoxidil stimulates cutaneous blood flow in human balding scalps: Pharmacodynamics measured by laser Doppler velocimetry and photopulse plethysmography . J Invest Dermatol 1984; 82:515-517.Crossref 11. Vanderveen EE, Ellis CN, Kang S, et al: Topical minoxidil for hair regrowth . J Am Acad Dermatol 1984;11:416-421.Crossref 12. Olsen EA, Weiner MS, Delong ER, et al: Topical minoxidil in early male pattern baldness . J Am Acad Dermatol 1985;13:185-192.Crossref

Journal

Archives of Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Aug 1, 1988

References