Abstract • Cryptosporidiosis is increasingly recognized as a significant human pathogen. Previous reports have emphasized the benign, self-limited nature of the illness in the immunocompetent adult. In contrast, immunodeficient hosts have severe, frequently unremitting illness. We describe a case in which an individual, with no evidence of immunodeficiency and negative human immunodeficiency virus serologic findings, was admitted with a five-week history of severe diarrhea, marked weight loss, and renal failure probably as a consequence of cryptosporidiosis. The patient's renal function returned to normal with hydration, and his diarrhea resolved without specific therapy. At a six-month follow-up, the patient was in excellent health. (Arch Intern Med 1988;148:1873-1874) References 1. Schultz MG: Emerging zoonoses. N Engl J Med 1983;308:1285-1286.Crossref 2. Current WL, Reese NC, Ernst JV, et al: Human cryptosporidiosis in immunocompetent and immunodeficient persons: Studies of an outbreak and experimental transmission. N Engl J Med 1983;308:1252-1257.Crossref 3. Pitlik SD, Fainstein V, Garza D, et al: Human cryptosporidiosis: Spectrum of disease, report of six cases, and review of the literature. Arch Intern Med 1983;143:2269-2275.Crossref 4. Wolfson JS, Richter JM, Waldron MA, et al: Cryptosporidiosis in immunocompetent patients. N Engl J Med 1985;312:1278-1281.Crossref 5. Hunt DA, Shannon R, Palmer SR, et al: Cryptosporidiosis in an urban community. Br Med J 1984;289:814-816.Crossref 6. Hart CA, Baxby D, Blundell N: Gastroenteritis due to cryptosporidium: A prospective survey in a children's hospital. J Infect 1984;9:264-270.Crossref 7. Alpert G, Bell LM, Kirkpatrick CE, et al: Outbreak of cryptosporidiosis in a day-care center. Pediatrics 1986;77:152-157. 8. Soave R, Danner RL, Honig CL, et al: Cryptosporidiosis in homosexual men. Ann Intern Med 1984;100:504-511.Crossref 9. Poonacha KB, Pippin C: Intestinal cryptosporidiosis in a cat. Vet Pathol 1982;19:708-710.Crossref 10. Anderson BC, Donndelinger T, Wilkins RM, et al: Cryptosporidiosis in a veterinary student. J Am Vet Med Assoc 1982;180:408-409. 11. Navin TR, Juranok DD: Cryptosporidiosis: Clinical, epidemiologic and parasitologic review. Rev Infect Dis 1984;6:313-327.Crossref 12. Hart CA, Baxby D: Cryptosporidiosis in immunocompetent patients. N Engl J Med 1983;313:1018.
Archives of Internal Medicine – American Medical Association
Published: Aug 1, 1988
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