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Sequestered Substernal Goiter

Sequestered Substernal Goiter Abstract • A young woman with a normally located and only subtly nodular thyroid gland in the neck was found to have a clinically distinct and radioisotopically "cold" anterior mediastinal mass, which proved to be a benign colloid adenoma. While this constellation of findings usually suggests the presence of a nonthyroidal neoplasm, eg, lymphoma, thymoma, or teratoma, our case illustrates that sequestered benign nodular goiter should also be considered in the differential diagnosis. Clinical clues, such as a nodular thyroid gland, movement of the mass with deglutition, and a family history of nodular goiter, should suggest this possibility. A characteristic computed tomographic appearance may also prove useful in recognition of this rare disorder. (Arch Intern Med 1983;143:1015-1017) References 1. Rogers WM: Anomalous development of the thyroid , in Werner SC, Ingbar SH (eds): The Thyroid: A Fundamental and Clinical Test , ed 4. Hagerstown, Md, Harper & Row, 1978, pp 416-420. 2. Ellis FH, Good CA: Intrathoracic goiter. Ann Surg 1952;135:79-90.Crossref 3. Irwin RS, Braman SS, Arvanitidis AN, et al: 131I thyroid scanning in preoperative diagnosis of mediastinal goiter. Ann Intern Med 1978;89:73-74.Crossref 4. Sisson JC, Schmidt RW, Beierwaltes WH: Sequestered nodular goiter. N Engl J Med 1964;270:927-932.Crossref 5. Rives JD: Mediastinal aberrant goiter. Ann Surg 1947;126:797-810.Crossref 6. Dundas P: Intrathoracic aberrant goiter. Acta Clin Scand 1964;128: 729-736. 7. Kaplan WD, Watnick M, Holman BL: Scintigraphic identification of complete thoracic goiter with normal-appearing cervical thyroid: A case report. J Can Assoc Radiol 1974;25:193-195. 8. Pemberton JJ, Matiorner HR: Retrofascial intrathoracic goiter: Congenital hemolytic icterus: Retroperitoneal cyst. Surg Clin North Am 1931;11:787-799. 9. Maloof F, Wang CA, Vickery AL Jr: Nontoxic goiter: Diffuse or nodular. Med Clin North Am 1975;59:1221-1232. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1983 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1983.00350050179031
Publisher site
See Article on Publisher Site

Abstract

Abstract • A young woman with a normally located and only subtly nodular thyroid gland in the neck was found to have a clinically distinct and radioisotopically "cold" anterior mediastinal mass, which proved to be a benign colloid adenoma. While this constellation of findings usually suggests the presence of a nonthyroidal neoplasm, eg, lymphoma, thymoma, or teratoma, our case illustrates that sequestered benign nodular goiter should also be considered in the differential diagnosis. Clinical clues, such as a nodular thyroid gland, movement of the mass with deglutition, and a family history of nodular goiter, should suggest this possibility. A characteristic computed tomographic appearance may also prove useful in recognition of this rare disorder. (Arch Intern Med 1983;143:1015-1017) References 1. Rogers WM: Anomalous development of the thyroid , in Werner SC, Ingbar SH (eds): The Thyroid: A Fundamental and Clinical Test , ed 4. Hagerstown, Md, Harper & Row, 1978, pp 416-420. 2. Ellis FH, Good CA: Intrathoracic goiter. Ann Surg 1952;135:79-90.Crossref 3. Irwin RS, Braman SS, Arvanitidis AN, et al: 131I thyroid scanning in preoperative diagnosis of mediastinal goiter. Ann Intern Med 1978;89:73-74.Crossref 4. Sisson JC, Schmidt RW, Beierwaltes WH: Sequestered nodular goiter. N Engl J Med 1964;270:927-932.Crossref 5. Rives JD: Mediastinal aberrant goiter. Ann Surg 1947;126:797-810.Crossref 6. Dundas P: Intrathoracic aberrant goiter. Acta Clin Scand 1964;128: 729-736. 7. Kaplan WD, Watnick M, Holman BL: Scintigraphic identification of complete thoracic goiter with normal-appearing cervical thyroid: A case report. J Can Assoc Radiol 1974;25:193-195. 8. Pemberton JJ, Matiorner HR: Retrofascial intrathoracic goiter: Congenital hemolytic icterus: Retroperitoneal cyst. Surg Clin North Am 1931;11:787-799. 9. Maloof F, Wang CA, Vickery AL Jr: Nontoxic goiter: Diffuse or nodular. Med Clin North Am 1975;59:1221-1232.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: May 1, 1983

References