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Selective vs Nonselective Nonsteroidal Anti-inflammatory Drugs and Anastomotic Leakage After Colorectal Surgery

Selective vs Nonselective Nonsteroidal Anti-inflammatory Drugs and Anastomotic Leakage After... Letters 6. Hind D, Wyld L, Beverley CB, Reed MW. Surgery versus primary endocrine Our patient population was largely positive for ER, but only therapy for operable primary breast cancer in elderly women (70 years plus). 40% received hormonal therapy. Despite this, only 4% of pa- Cochrane Database Syst Rev. 2006;(1):CD004272. tients experienced a breast cancer–related event. Not performing a sentinel node biopsy may avoid poten- tial morbidity and should be reevaluated for patients 70 years of age or older with clinically negative nodes. Patients were un- COMMENT & RESPONSE likely to have treatment recommendations changed based on Selective vs Nonselective Nonsteroidal a sentinel node biopsy, and adjuvant therapy was less likely Anti-inflammatory Drugs and Anastomotic Leakage to be administered, regardless of nodal status. Patients in this After Colorectal Surgery subgroup were more likely to die of causes other than breast To the Editor We read with interest the article by Hakkarainen cancer, and not performing a sentinel node biopsy did not affect survival. et al and wish to commend the authors on their attempt to shed light on the challenging question of nonsteroidal anti- inflammatory drugs (NSAIDs) and the risk for anastomotic leak- Alice Chung, MD age after http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

Selective vs Nonselective Nonsteroidal Anti-inflammatory Drugs and Anastomotic Leakage After Colorectal Surgery

Lynch, Noel P.; Boyle, Emily; Kavanagh, Eamon G.
JAMA Surgery , Volume 150 (7) – Jul 1, 2015
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Publisher
American Medical Association
Copyright
Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/jamasurg.2015.0641
pmid
25946009
Publisher site
See Article on Publisher Site

Abstract

Letters 6. Hind D, Wyld L, Beverley CB, Reed MW. Surgery versus primary endocrine Our patient population was largely positive for ER, but only therapy for operable primary breast cancer in elderly women (70 years plus). 40% received hormonal therapy. Despite this, only 4% of pa- Cochrane Database Syst Rev. 2006;(1):CD004272. tients experienced a breast cancer–related event. Not performing a sentinel node biopsy may avoid poten- tial morbidity and should be reevaluated for patients 70 years of age or older with clinically negative nodes. Patients were un- COMMENT & RESPONSE likely to have treatment recommendations changed based on Selective vs Nonselective Nonsteroidal a sentinel node biopsy, and adjuvant therapy was less likely Anti-inflammatory Drugs and Anastomotic Leakage to be administered, regardless of nodal status. Patients in this After Colorectal Surgery subgroup were more likely to die of causes other than breast To the Editor We read with interest the article by Hakkarainen cancer, and not performing a sentinel node biopsy did not affect survival. et al and wish to commend the authors on their attempt to shed light on the challenging question of nonsteroidal anti- inflammatory drugs (NSAIDs) and the risk for anastomotic leak- Alice Chung, MD age after

Journal

JAMA Surgery – American Medical Association

Published: Jul 1, 2015

References

  • Nonsteroidal anti-inflammatory drugs and the risk for anastomotic failure: a report from Washington State’s Surgical Care and Outcomes Assessment Program (SCOAP).
    Hakkarainen, TW; Steele, SR; Bastaworous, A
  • Risk of anastomotic leakage with non-steroidal anti-inflammatory drugs in colorectal surgery.
    Gorissen, KJ; Benning, D; Berghmans, T
  • Why most published research findings are false.
    Ioannidis, JP
  • Why bigger is not yet better: the problems with huge datasets.