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Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy—This Time It’s Personal

Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy—This Time It’s Personal Opinion EDITORIAL Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy—This Time It’s Personal Vernon K. Sondak, MD; Jane L. Messina, MD; Jonathan S. Zager, MD Thin (T1) melanomas, defined in the 8th edition of the Ameri- dergoing the procedure. Understandably, the controversy over selection of patients with thin melanomas for SLNB rages on. can Joint Committee on Cancer (AJCC) Cancer Staging Manual for melanomaasanyprimarycutaneousmelanomaofBreslowthick- In a retrospective review of data from the National Cancer ness 1.0 mm or thinner, account for more than 70% of newly di- Data Base published in this issue of JAMA Dermatology, 2 11 agnosed cutaneous melanoma in the United States. (The AJCC Sinnamon and colleagues analyzed the rate of lymph node posi- CancerStagingManual,8thedition,stagingsystemformelanoma tivity in 8772 patients with thin melanomas (0.5-1.0 mm) with mandatesreportingofBreslow an eye toward refining our current recommendations for SLNB. thickness measurements to They found that 333 patients (3.8%; 95% CI, 3.4%-4.2%) had at Related article page 866 the nearest 0.1 mm, not the least 1 positive lymph node. If the widely used threshold of nearest 0.01 mm, and this con- requiring at least a 5% probability of finding a positive node to ventionwillbeusedinthiseditorial.TheAJCCrecommendsmea- justify performing SLNB is applied, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy—This Time It’s Personal

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Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/jamadermatol.2017.2496
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy—This Time It’s Personal Vernon K. Sondak, MD; Jane L. Messina, MD; Jonathan S. Zager, MD Thin (T1) melanomas, defined in the 8th edition of the Ameri- dergoing the procedure. Understandably, the controversy over selection of patients with thin melanomas for SLNB rages on. can Joint Committee on Cancer (AJCC) Cancer Staging Manual for melanomaasanyprimarycutaneousmelanomaofBreslowthick- In a retrospective review of data from the National Cancer ness 1.0 mm or thinner, account for more than 70% of newly di- Data Base published in this issue of JAMA Dermatology, 2 11 agnosed cutaneous melanoma in the United States. (The AJCC Sinnamon and colleagues analyzed the rate of lymph node posi- CancerStagingManual,8thedition,stagingsystemformelanoma tivity in 8772 patients with thin melanomas (0.5-1.0 mm) with mandatesreportingofBreslow an eye toward refining our current recommendations for SLNB. thickness measurements to They found that 333 patients (3.8%; 95% CI, 3.4%-4.2%) had at Related article page 866 the nearest 0.1 mm, not the least 1 positive lymph node. If the widely used threshold of nearest 0.01 mm, and this con- requiring at least a 5% probability of finding a positive node to ventionwillbeusedinthiseditorial.TheAJCCrecommendsmea- justify performing SLNB is applied,

Journal

JAMA DermatologyAmerican Medical Association

Published: Sep 19, 2017

References