Abstract To the Editor.— This letter describes a case of secondary syphilis and sarcoidosis, which had been diagnosed radiologically. Report of a Case.— A 25-year-old woman had been under the care of a pulmonary specialist since December 1972; at that time, nodular densities in both lung fields were noted and a diagnosis of sarcoidosis was made. Previous chest x-ray films taken in June 1972 were normal and the VDRL test for syphilis and the fluorescent treponemal antibody absorption test for syphilis (FTA-ABS) were nonreactive. In February 1973, two percutaneous lung biopsy specimens showed no evidence of granulomatous disease. Cultures of biopsy material were negative for tuberculosis and the patient did not report for reading of the purified protein derivative, monilial, or fungal skin tests. Since the patient had lived in Detroit, Mich all of her life, histoplasmosis and coccidioidomycosis were considered unlikely causal agents. On June 15, 1973, she came to References 1. Lomholt G: Syphilis, in Rook A, Wilkinson DS, Ebling FG (eds): Textbook of Dermatology . Oxford, England, Blackwell Scientific Publications, 1972, pp 634-638. 2. O'Lansky S, Norins LC: Syphilis and other treponematoses , in Fitzpatrick TB, Arndt KA, Clark WH Jr, et al (eds): Dermatology in General Medicine . New York, McGraw-Hill Book Co Inc, 1971, pp 1955-1978. 3. Lever WH: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1967. 4. Pinkus H, Mehregan AH: A Guide to Dermatopathology . New York, Appleton-Century-Crofts, 1969. 5. Jeerapaet P, Ackerman AB: Histological patterns of secondary syphilis . Arch Dermatol 104:373-377, 1973.Crossref 6. Lochner JC, Pomeranz JR: Lichenoid secondary syphilis . Arch Dermatol 109:81-83, 1974.Crossref 7. Miller RL: Pustular secondary syphilis . Bull Assoc Milit Dermatol 21:24-27, 1973. 8. Mikhail GR, Chapel TA: Follicular papulopustular syphilid . Arch Dermatol 100:471-473, 1969.Crossref 9. Van Dersarb JV: Granulomatous secondary syphilis . Bull Assoc Milit Dermatol 19:25-27, 1971. 10. Sing R, Kaur D, Parameswaran M: Sarcoidal reaction of the skin in syphilis . Br J Vener Dis 47:209-211, 1971. 11. Stillians AW: Sarcoid and syphilis . JAMA 77:1615-1618, 1921.Crossref 12. Frazier CN, Ch'uan-k'uei H: Isolation of treponema pallidum from a subcutaneous sarcoid . Proc Soc Exp Biol Med 30:898-901, 1933.Crossref 13. Berstein ET, Leider M: Cutaneous sarcoidosis as an expression of syphilis . J Invest Dermatol 15:75-79, 1950.Crossref
Archives of Dermatology – American Medical Association
Published: Feb 1, 1975
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