Abstract The coexistence of xanthomata with lipoid nephrosis is rare in the literature. This combination, with the xanthomata located within a telangiectatic vascular naevus unius lateris, has never been previously reported. Although numerous cases of secondary eruptive xanthomata associated with hyperlipemia, of specific or idiopathic origin, have been described,1 careful search discloses but three references to such an eruption associated with lipoid nephrosis.* Unilateral nevi have been reported as lichenoid,5 comedonicus,† tardus,9 verrucous,10 and eczematous11 varieties. A case of telangiectatic vascular naevus unius lateris, however, has not been reported. Since the occurrence of eruptive xanthoma is a manifestation of underlying hyperlipemia,1 which is constant in lipoid nephrosis, the paucity of reports of associated xanthomata is interesting. The occurrence of such xanthomatous lesions, almost entirely within the area of great vascularity of the nevus, adds to the importance of the References 1. References 2, 3, and 4. 2. References 6, 7, and 8. 3. Thannhauser, S. J.: Lipidoses: Diseases of the Cellular Lipid Metabolism , edited by H. A. Christian, Ed. 2, New York, Oxford University Press, 1950, p. 214. 4. Friedman, R.; Nelson, W. E.; Stritzler, C., and Roxby, J. B., Jr.: Xanthoma Eruptivum Secondary to Lipoid Nephrosis , Arch. Dermat. & Syph. 60:828, 1949. 5. Crocker, A. C.: Skin Xanthomas in Childhood , Pediatrics 8:573, 1951. 6. Taylor, W. B., and Curtis, A. C.: Hyperlipemic Xanthomatosis in a Patient with Subacute Glomerulonephritis (Nephrotic Stage) , A. M. A. Arch. Dermat. & Syph. 70:518, 1954. 7. Bechet, P. E.: Naevus Unius Lateris, Simulating Linear Lichen Planus , Arch. Dermat. & Syph. 40:620, 1939. 8. Gougerot and Burnier: Naevus linéaire à comédons (nevus vermonlant) , Bull. Soc. franç., dermat. et syph. 42:589, 1935. 9. Noraeus, S.: Fall av naevus comedonicus atroficans unilateralis , Nord. med. 12:3377, 1941. 10. Touraine: Grand naevus linéaire de type comédon et atrophique (femme de 53 ans) , Ann. dermat. et syph. Vol. 7, Fig. 59, between pp. 140 and 141, 1947. 11. Oliver, E., A, and Bluefarb, S. M.: Naevus Unilateralis Tardus , Arch. Dermat. & Syph. 46: 315, 1942. 12. Kopp, C.: Zur Kasuistik des Naevus vasculosus verrucosus faciei (Darier) , Deutsches Arch. klin. Med. 84:135, 1905. 13. Weise, E. C.: Naevus Linearis (Naevus Unius Lateralis): Eczematous Nevus , Arch. Dermat. & Syph. 31:575, 1935.
A.M.A. Archives of Dermatology – American Medical Association
Published: Sep 1, 1955