Seborrheic Distributed Papules With Palmoplantar Hyperkeratosis—Diagnosis
Abstract
Diagnosis: Ichthyosis hystrix, Curth-Macklin type. Microscopic findings and clinical findings Microscopic sections revealed papillomatosis and compact orthokeratotic hyperkeratosis. The granular layer was markedly thickened, with vacuolated keratinocytes exhibiting perinuclear edema and numerous binucleate cells. No significant epidermolysis or acantholysis was seen. Other family members had had similar clinical presentations and had previously been studied, although this information was not...