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Searching for Treatments of Heart Failure With Preserved Ejection Fraction

Searching for Treatments of Heart Failure With Preserved Ejection Fraction Opinion Editorials represent the opinions of the authors and JAMA EDITORIAL and not those of the American Medical Association. Searching for Treatments of Heart Failure With Preserved Ejection Fraction Matching the Data to the Question Susan Cheng, MD, MPH; Marc A. Pfeffer, MD, PhD Heart failure with preserved ejection fraction (HFPEF) poses tiple characteristics in the cohort. Therefore, to compare out- just as daunting a challenge for physicians and patients as heart comes between treated and nontreated individuals, a propen- failure with reduced ejection fraction (HFREF) but without sity score–matching process was required to create a subsample nearly as defined a course for of treated and untreated patients who appeared more bal- how to best treat affected pa- anced in terms of their demographic and clinical characteris- tients. Although potential tics. Ultimately, a total of 8244 patients were matched 2:1 Related article page 2008 new therapies for treating (β-blocker:no β-blocker) based on age, sex, and propensity for HFPEF are being investigated, it is always worth revisiting ex- being prescribed a β-blocker. When the matched groups were isting therapies to evaluate their potential as available and cost- compared, presence of β-blocker therapy was associated with effective options for care. This http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Searching for Treatments of Heart Failure With Preserved Ejection Fraction

JAMA , Volume 312 (19) – Nov 19, 2014

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Publisher
American Medical Association
Copyright
Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2014.15358
pmid
25399271
Publisher site
See Article on Publisher Site

Abstract

Opinion Editorials represent the opinions of the authors and JAMA EDITORIAL and not those of the American Medical Association. Searching for Treatments of Heart Failure With Preserved Ejection Fraction Matching the Data to the Question Susan Cheng, MD, MPH; Marc A. Pfeffer, MD, PhD Heart failure with preserved ejection fraction (HFPEF) poses tiple characteristics in the cohort. Therefore, to compare out- just as daunting a challenge for physicians and patients as heart comes between treated and nontreated individuals, a propen- failure with reduced ejection fraction (HFREF) but without sity score–matching process was required to create a subsample nearly as defined a course for of treated and untreated patients who appeared more bal- how to best treat affected pa- anced in terms of their demographic and clinical characteris- tients. Although potential tics. Ultimately, a total of 8244 patients were matched 2:1 Related article page 2008 new therapies for treating (β-blocker:no β-blocker) based on age, sex, and propensity for HFPEF are being investigated, it is always worth revisiting ex- being prescribed a β-blocker. When the matched groups were isting therapies to evaluate their potential as available and cost- compared, presence of β-blocker therapy was associated with effective options for care. This

Journal

JAMAAmerican Medical Association

Published: Nov 19, 2014

References