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Sea-Blue Histiocytosis: A New Cause of Malabsorption Syndrome?

Sea-Blue Histiocytosis: A New Cause of Malabsorption Syndrome? Abstract To the Editor. —Since the first description of Silverstein et al1 in 1970 of the syndrome of the sea-blue histiocyte, over 70 cases of the primary and often familial disease have been published in world literature. All of them characteristically affect diverse organs of the reticuloendothelial system, principally liver, spleen, and bone marrow, and deal with more or less common symptoms.2 Other than in the hereditary syndrome, sea-blue histiocytes have been identified in bone marrow or spleen of patients with an impressive variety of hematologic and metabolic abnormalities.3 In 1972, Silverstein and Ellefson4 had proposed criteria for the diagnosis of the primary form of the sea-blue histiocytosis. We have recently been able to study a new case of the hereditary syndrome in which, for the first time, the involvement of the intestinal mucosa has been verified, having observed a pronounced infiltration by sea-blue histiocytes in its References 1. Silverstein MN, Ellefson RD, Ahern E: The syndrome of the sea-blue histiocyte. N Engl J Med 282:1-4, 1970.Crossref 2. Sawitsky A, Rosner F, Chodsky S: The sea-blue histiocyte syndrome, a review: Genetic and biochemical studies. Semin Hematol 9:285-297, 1972. 3. Mason BA, Bowers GR, Guccion JG, et al: Sea-blue histiocytes in a patient with lymphoma. Am J Med 64:515-518, 1978.Crossref 4. Silverstein MN, Ellefson RD: The syndrome of the sea-blue histiocyte. Semin Hematol 9:299-307, 1972. 5. Espinós D, Alba J, Alvarez-Sala JL, et al: Afectación intestinal en el síndrome del histiocito azul marino. Sangre , to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Sea-Blue Histiocytosis: A New Cause of Malabsorption Syndrome?

Sea-Blue Histiocytosis: A New Cause of Malabsorption Syndrome?

Abstract

Abstract To the Editor. —Since the first description of Silverstein et al1 in 1970 of the syndrome of the sea-blue histiocyte, over 70 cases of the primary and often familial disease have been published in world literature. All of them characteristically affect diverse organs of the reticuloendothelial system, principally liver, spleen, and bone marrow, and deal with more or less common symptoms.2 Other than in the hereditary syndrome, sea-blue histiocytes have been identified in bone...
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Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1980.00330160144059
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor. —Since the first description of Silverstein et al1 in 1970 of the syndrome of the sea-blue histiocyte, over 70 cases of the primary and often familial disease have been published in world literature. All of them characteristically affect diverse organs of the reticuloendothelial system, principally liver, spleen, and bone marrow, and deal with more or less common symptoms.2 Other than in the hereditary syndrome, sea-blue histiocytes have been identified in bone marrow or spleen of patients with an impressive variety of hematologic and metabolic abnormalities.3 In 1972, Silverstein and Ellefson4 had proposed criteria for the diagnosis of the primary form of the sea-blue histiocytosis. We have recently been able to study a new case of the hereditary syndrome in which, for the first time, the involvement of the intestinal mucosa has been verified, having observed a pronounced infiltration by sea-blue histiocytes in its References 1. Silverstein MN, Ellefson RD, Ahern E: The syndrome of the sea-blue histiocyte. N Engl J Med 282:1-4, 1970.Crossref 2. Sawitsky A, Rosner F, Chodsky S: The sea-blue histiocyte syndrome, a review: Genetic and biochemical studies. Semin Hematol 9:285-297, 1972. 3. Mason BA, Bowers GR, Guccion JG, et al: Sea-blue histiocytes in a patient with lymphoma. Am J Med 64:515-518, 1978.Crossref 4. Silverstein MN, Ellefson RD: The syndrome of the sea-blue histiocyte. Semin Hematol 9:299-307, 1972. 5. Espinós D, Alba J, Alvarez-Sala JL, et al: Afectación intestinal en el síndrome del histiocito azul marino. Sangre , to be published.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Apr 1, 1980

References