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Screening for Colorectal Cancer: Which Test Is Best?-Reply

Screening for Colorectal Cancer: Which Test Is Best?-Reply In Reply. —Dr Mandel and colleagues provide new data from the Minnesota Colon Cancer Control Study and observe correctly that these data could be used to further elucidate the mechanism by which FOBT screening with slide rehydration reduces CRC mortality. We agree that the cumulative rate of colonoscopy in the screened group will have an important effect on any projection of the degree to which random screening colonoscopy, done for workup of false-positive FOBT results, contributes to CRC mortality reductions. The values used in our model were based on the published data.1 We agree that the results also depend on the degree and duration of protective effect from endoscopy screening, so we provided tables showing results for different durations and degrees of protection from endoscopy screening. New insights from the Minnesota study's data might be obtained by considering the types of neoplasms detected in the screened group (ie, early http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Screening for Colorectal Cancer: Which Test Is Best?-Reply

Lang, Christopher A.; Ransohoff, David F.
JAMA , Volume 272 (14) – Oct 12, 1994
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Screening for Colorectal Cancer: Which Test Is Best?-Reply

Abstract



In Reply.
—Dr Mandel and colleagues provide new data from the Minnesota Colon Cancer Control Study and observe correctly that these data could be used to further elucidate the mechanism by which FOBT screening with slide rehydration reduces CRC mortality. We agree that the cumulative rate of colonoscopy in the screened group will have an important effect on any projection of the degree to which random screening colonoscopy, done for workup of false-positive FOBT results, contributes...
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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1994 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1994.03520140029019
Publisher site
See Article on Publisher Site

Abstract

In Reply. —Dr Mandel and colleagues provide new data from the Minnesota Colon Cancer Control Study and observe correctly that these data could be used to further elucidate the mechanism by which FOBT screening with slide rehydration reduces CRC mortality. We agree that the cumulative rate of colonoscopy in the screened group will have an important effect on any projection of the degree to which random screening colonoscopy, done for workup of false-positive FOBT results, contributes to CRC mortality reductions. The values used in our model were based on the published data.1 We agree that the results also depend on the degree and duration of protective effect from endoscopy screening, so we provided tables showing results for different durations and degrees of protection from endoscopy screening. New insights from the Minnesota study's data might be obtained by considering the types of neoplasms detected in the screened group (ie, early

Journal

JAMA – American Medical Association

Published: Oct 12, 1994

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