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SCLERODERMA AND SCLERODACTYLIA ASSOCIATED WITH INTERMITTENT CLAUDICATION

SCLERODERMA AND SCLERODACTYLIA ASSOCIATED WITH INTERMITTENT CLAUDICATION Abstract During the past few years the etiology of scleroderma has received considerable attention from European and American investigators. Among many of the possible causes, the glands of internal secretion1 and the sympathetic nervous system2 have been considered both separately and together as playing important rôles in the production of the pathologic changes noted in this disease. Osler1i and Oliver,3 however, have summed up the actual knowledge as to the source of scleroderma in the statement that little progress has been made in determining its exact cause. Sclerodactylia has been classified as an angiotrophoneurosis related to endocrine disturbance and to dysfunction of the sympathetic nervous system.4 Sellei5 has recently suggested dysfunctions of ferment-producing organs, principally the pancreas, as etiologic agents in scleroderma and sclerodactylia and has advocated the administration of pancreatic, duodenal and gastric ferments for the relief of the vascular spasm, especially when associated References 1. Strunz, F.: Ein Fall von Progeria, beginnend mit ausgedehnter Sklerodermie , Ztschr. f. Kinderh. 47:401, 1929.Crossref 2. Strümpell, A.: Ein Beitrag zur Pathologie und pathologischen Anatomie der Acromegalie , Deutsche Ztschr. f. Nervenh. 11:51, 1897.Crossref 3. Sequeira, J. H.: Four Cases of Scleroderma Associated with Disease of the Thyroid Gland , Brit. J. Dermat. 28:31, 1916.Crossref 4. Longcope, W. T.: Hypoglycemia in Scleroderma: Metabolism in Eight Cases with Reference to Function of Glands of Internal Secretion , J. A. M. A. 90:1 ( (Jan. 7) ) 1928.Crossref 5. O'Leary, P. A., and Nomland, R.: A Clinical Study of One Hundred and Three Cases of Scleroderma , Am. J. M. Sc. 180:95, 1930.Crossref 6. Castle, W. F.: The Endocrine Causation of Scleroderma , Brit. J. Dermat. 35:255 and 303, 1923.Crossref 7. Hoffmann, H.: Untersuchungen über endokrine Störungen bei Hautkrankheiten, insbesondere Sklerodermie und Acrodermatitis atrophicans , Acta dermat.-venereol. 6:423, 1925. 8. Foerster, O. H.: Relation of Internal Secretions to Cutaneous Disease , J. Cutan. Dis. 34:1, 1916. 9. Osier, W.: On Diffuse Scleroderma with Special Reference to Diagnosis and to the Use of Thyroid Gland Extract , J. Cutan. Dis. 16:49, 1898. 10. Adson, A. W., and Brown, G. E.: Thoracic and Lumbar Sympathetic Ganglionectomy in Peripheral Vascular Diseases: Therapeutic Value , J. A. M. A. 94:250 ( (Jan. 25) ) 1930.Crossref 11. Baissaud, E.: Pathogénie du processus sclérodermique , Presse méd. 51:285, 1897. 12. Oliver, E. L.: Generalized Scleroderma in Children , Arch. Dermat. & Syph. 25:72 ( (Jan.) ) 1932. 13. Hoffmann.1g Adson and Brown.2a Oliver.3 14. Sellei, J.: Weitere Beiträge zur Fermenttherapie des Skleroderma , Arch. f. Dermat. u. Syph. 171:577, 1935. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

SCLERODERMA AND SCLERODACTYLIA ASSOCIATED WITH INTERMITTENT CLAUDICATION

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Publisher
American Medical Association
Copyright
Copyright © 1937 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1937.01480050120017
Publisher site
See Article on Publisher Site

Abstract

Abstract During the past few years the etiology of scleroderma has received considerable attention from European and American investigators. Among many of the possible causes, the glands of internal secretion1 and the sympathetic nervous system2 have been considered both separately and together as playing important rôles in the production of the pathologic changes noted in this disease. Osler1i and Oliver,3 however, have summed up the actual knowledge as to the source of scleroderma in the statement that little progress has been made in determining its exact cause. Sclerodactylia has been classified as an angiotrophoneurosis related to endocrine disturbance and to dysfunction of the sympathetic nervous system.4 Sellei5 has recently suggested dysfunctions of ferment-producing organs, principally the pancreas, as etiologic agents in scleroderma and sclerodactylia and has advocated the administration of pancreatic, duodenal and gastric ferments for the relief of the vascular spasm, especially when associated References 1. Strunz, F.: Ein Fall von Progeria, beginnend mit ausgedehnter Sklerodermie , Ztschr. f. Kinderh. 47:401, 1929.Crossref 2. Strümpell, A.: Ein Beitrag zur Pathologie und pathologischen Anatomie der Acromegalie , Deutsche Ztschr. f. Nervenh. 11:51, 1897.Crossref 3. Sequeira, J. H.: Four Cases of Scleroderma Associated with Disease of the Thyroid Gland , Brit. J. Dermat. 28:31, 1916.Crossref 4. Longcope, W. T.: Hypoglycemia in Scleroderma: Metabolism in Eight Cases with Reference to Function of Glands of Internal Secretion , J. A. M. A. 90:1 ( (Jan. 7) ) 1928.Crossref 5. O'Leary, P. A., and Nomland, R.: A Clinical Study of One Hundred and Three Cases of Scleroderma , Am. J. M. Sc. 180:95, 1930.Crossref 6. Castle, W. F.: The Endocrine Causation of Scleroderma , Brit. J. Dermat. 35:255 and 303, 1923.Crossref 7. Hoffmann, H.: Untersuchungen über endokrine Störungen bei Hautkrankheiten, insbesondere Sklerodermie und Acrodermatitis atrophicans , Acta dermat.-venereol. 6:423, 1925. 8. Foerster, O. H.: Relation of Internal Secretions to Cutaneous Disease , J. Cutan. Dis. 34:1, 1916. 9. Osier, W.: On Diffuse Scleroderma with Special Reference to Diagnosis and to the Use of Thyroid Gland Extract , J. Cutan. Dis. 16:49, 1898. 10. Adson, A. W., and Brown, G. E.: Thoracic and Lumbar Sympathetic Ganglionectomy in Peripheral Vascular Diseases: Therapeutic Value , J. A. M. A. 94:250 ( (Jan. 25) ) 1930.Crossref 11. Baissaud, E.: Pathogénie du processus sclérodermique , Presse méd. 51:285, 1897. 12. Oliver, E. L.: Generalized Scleroderma in Children , Arch. Dermat. & Syph. 25:72 ( (Jan.) ) 1932. 13. Hoffmann.1g Adson and Brown.2a Oliver.3 14. Sellei, J.: Weitere Beiträge zur Fermenttherapie des Skleroderma , Arch. f. Dermat. u. Syph. 171:577, 1935.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Nov 1, 1937

References