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School Classrooms as Targets to Reduce Allergens and Improve Asthma

School Classrooms as Targets to Reduce Allergens and Improve Asthma Opinion EDITORIAL William W. Busse, MD; Daniel J. Jackson, MD Aeroallergens are important components in the pathogenesis ronmental locale to consider. Targeting the classroom coin- and pathophysiology of asthma, with allergic sensitization a phe- cided with a growing interest in leveraging the school in child- 1 10-12 notypic component and risk factor for disease severity. Aeroal- hood asthma management programs. The next step was lergens provoke airway inflammation, cause airflow obstruction, to identify an intervention model. and create risks for exacerba- An integrated pest management (IPM) intervention in- tions of asthma. Guideline- cludes extermination and sealing holes to prevent mouse en- Related article page 839 directedtreatmentsforasthma try into the building. To evaluate the efficacy of these meth- target airway inflammation by prescribing anti-inflammatory ods, Matsui et al conducted a home-based study involving 361 medications, such as inhaled corticosteroids, to gain disease children who were randomized to an IPM plus education group control. Guidelines also recommend more holistic approaches or education alone for 1 year. Both treatment approaches to asthma control, including allergen avoidance. significantly reduced bedroom floor mouse allergen, but no sig- In contrast to a near-universal use of anti-inflammatory nificant changes were detected between the reduced bedroom medications http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

School Classrooms as Targets to Reduce Allergens and Improve Asthma

Busse, William W.; Jackson, Daniel J.
JAMA , Volume 326 (9) – Sep 7, 2021
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References (35)

Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2021.12322
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL William W. Busse, MD; Daniel J. Jackson, MD Aeroallergens are important components in the pathogenesis ronmental locale to consider. Targeting the classroom coin- and pathophysiology of asthma, with allergic sensitization a phe- cided with a growing interest in leveraging the school in child- 1 10-12 notypic component and risk factor for disease severity. Aeroal- hood asthma management programs. The next step was lergens provoke airway inflammation, cause airflow obstruction, to identify an intervention model. and create risks for exacerba- An integrated pest management (IPM) intervention in- tions of asthma. Guideline- cludes extermination and sealing holes to prevent mouse en- Related article page 839 directedtreatmentsforasthma try into the building. To evaluate the efficacy of these meth- target airway inflammation by prescribing anti-inflammatory ods, Matsui et al conducted a home-based study involving 361 medications, such as inhaled corticosteroids, to gain disease children who were randomized to an IPM plus education group control. Guidelines also recommend more holistic approaches or education alone for 1 year. Both treatment approaches to asthma control, including allergen avoidance. significantly reduced bedroom floor mouse allergen, but no sig- In contrast to a near-universal use of anti-inflammatory nificant changes were detected between the reduced bedroom medications

Journal

JAMA – American Medical Association

Published: Sep 7, 2021

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