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Schizophrenia-Primary Affective Disorder Discrimination: I. Development of a Data-Based Diagnostic Index

Schizophrenia-Primary Affective Disorder Discrimination: I. Development of a Data-Based... Abstract • A nine-variable diagnostic measure for discriminating schizophrenia and primary affective disorder was developed. The nine variables, which were selected by discriminant function analysis, reflect past and current symptomatology, duration of symptoms, and behavioral ratings. The measure was crossvalidated by a jackknife procedure that accurately classified nine of ten of the cases. Such accuracy suggests that brief, databased diagnostic instruments have considerable promise as practical checks of clinical diagnoses. References 1. Mellor CS: First-rank symptoms of schizophrenia . Br J Psychiatry 117:15-23, 1970. 2. Taylor MA: Schneiderian first-rank symptoms and clinical prognostic features in schizophrenia . Arch Gen Psychiatry 26:64-67, 1972.Crossref 3. Carpenter WT Jr, Strauss JS, Muleh S: Are there pathognomonic symptoms in schizophrenia? An empiric investigation of Schneider's firstrank symptoms . Arch Gen Psychiatry 28:847-852, 1973.Crossref 4. Fowler RC: Remitting schizophrenia as a variant of affective disorder . Schizophr Bull 4:68-77, 1978.Crossref 5. Pope HG Jr, Lipinski JF Jr: Diagnosis in schizophrenia and manicdepressive illness: A reassessment of the specificity of 'schizophrenic' symptoms in the light of current research . Arch Gen Psychiatry 35:811-828, 1978.Crossref 6. Feighner JP, Robins E, Guze SB, et al: Diagnostic criteria for use in psychiatric research . Arch Gen Psychiatry 25:57-63, 1972.Crossref 7. Spitzer RL, Endicott J, Robins E: Research diagnostic criteria: Rationale and reliability . Arch Gen Psychiatry 35:773-782, 1978.Crossref 8. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders , ed 3. Washington, DC, American Psychiatric Association, 1980, p 8. 9. Helzer JE, Clayton PJ, Pambakian R, et al: Concurrent diagnostic validity of a structured psychiatric interview . Arch Gen Psychiatry 35:849-853, 1978.Crossref 10. Endicott J, Spitzer RL: A diagnostic interview: The schedule for affective disorders and schizophrenia . Arch Gen Psychiatry 35:837-844, 1978.Crossref 11. Wing JK, Birley JLT, Cooper JE, et al: Reliability of a procedure for measuring and classifying 'present psychiatric state .' Br J Psychiatry 113:499-515, 1967.Crossref 12. Tsuang MT: The Iowa Structured Psychiatric Interview . Iowa City, Iowa, University of Iowa Press, 1974. 13. Kendell RE: The Role of Diagnosis in Psychiatry . Oxford, England, Blackwell Scientific Publications, 1975, p 150. 14. Overall JE, Higgins CW: An application of actuarial methods in psychiatric diagnosis . J Clin Psychol 33:973-980, 1977.Crossref 15. Kendell RE, Gourlay J: The clinical distinction between the affective psychoses and schizophrenia . Br J Psychiatry 117:261-266, 1970. 16. Brockington IF, Kendell RE, Wainwright S, et al: The distinction between the affective psychoses and schizophrenia . Br J Psychiatry 135:243-248, 1979.Crossref 17. Carpenter WT Jr, Strauss JS, Bartko JJ: Flexible system for the diagnosis of schizophrenia: Report from the WHO International Pilot Study of Schizophrenia . Science 182:1275-1278, 1973.Crossref 18. Fowler RC, Liskow BI, Tanna VL, et al: Psychiatric illness and alcoholism . Alcoholism 1:125-128, 1977.Crossref 19. Dixon WJ (ed): Biomedical Computer Programs . Berkeley, University of California Press, 1977, pp 711-740. 20. Lachenbruch PA, Mickey MR: Estimation of error rates in discriminant analysis . Technometrics 10:1-11, 1968.Crossref 21. Carey G, Gottesman II: Reliability and validity in binary ratings: Areas of common misunderstanding in diagnosis and symptom ratings . Arch Gen Psychiatry 35:1454-1459, 1978.Crossref 22. Fleiss JL, Spitzer RL, Cohen J, et al: Three computer diagnosis methods compared . Arch Gen Psychiatry 27:643-649, 1972.Crossref 23. Melrose JP, Stroebel CF, Glueck BC: Diagnosis of psychopathology using stepwise multiple discriminant analysis . Compr Psychiatry 11:43-50, 1970.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

Schizophrenia-Primary Affective Disorder Discrimination: I. Development of a Data-Based Diagnostic Index

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Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1980.01780200089010
Publisher site
See Article on Publisher Site

Abstract

Abstract • A nine-variable diagnostic measure for discriminating schizophrenia and primary affective disorder was developed. The nine variables, which were selected by discriminant function analysis, reflect past and current symptomatology, duration of symptoms, and behavioral ratings. The measure was crossvalidated by a jackknife procedure that accurately classified nine of ten of the cases. Such accuracy suggests that brief, databased diagnostic instruments have considerable promise as practical checks of clinical diagnoses. References 1. Mellor CS: First-rank symptoms of schizophrenia . Br J Psychiatry 117:15-23, 1970. 2. Taylor MA: Schneiderian first-rank symptoms and clinical prognostic features in schizophrenia . Arch Gen Psychiatry 26:64-67, 1972.Crossref 3. Carpenter WT Jr, Strauss JS, Muleh S: Are there pathognomonic symptoms in schizophrenia? An empiric investigation of Schneider's firstrank symptoms . Arch Gen Psychiatry 28:847-852, 1973.Crossref 4. Fowler RC: Remitting schizophrenia as a variant of affective disorder . Schizophr Bull 4:68-77, 1978.Crossref 5. Pope HG Jr, Lipinski JF Jr: Diagnosis in schizophrenia and manicdepressive illness: A reassessment of the specificity of 'schizophrenic' symptoms in the light of current research . Arch Gen Psychiatry 35:811-828, 1978.Crossref 6. Feighner JP, Robins E, Guze SB, et al: Diagnostic criteria for use in psychiatric research . Arch Gen Psychiatry 25:57-63, 1972.Crossref 7. Spitzer RL, Endicott J, Robins E: Research diagnostic criteria: Rationale and reliability . Arch Gen Psychiatry 35:773-782, 1978.Crossref 8. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders , ed 3. Washington, DC, American Psychiatric Association, 1980, p 8. 9. Helzer JE, Clayton PJ, Pambakian R, et al: Concurrent diagnostic validity of a structured psychiatric interview . Arch Gen Psychiatry 35:849-853, 1978.Crossref 10. Endicott J, Spitzer RL: A diagnostic interview: The schedule for affective disorders and schizophrenia . Arch Gen Psychiatry 35:837-844, 1978.Crossref 11. Wing JK, Birley JLT, Cooper JE, et al: Reliability of a procedure for measuring and classifying 'present psychiatric state .' Br J Psychiatry 113:499-515, 1967.Crossref 12. Tsuang MT: The Iowa Structured Psychiatric Interview . Iowa City, Iowa, University of Iowa Press, 1974. 13. Kendell RE: The Role of Diagnosis in Psychiatry . Oxford, England, Blackwell Scientific Publications, 1975, p 150. 14. Overall JE, Higgins CW: An application of actuarial methods in psychiatric diagnosis . J Clin Psychol 33:973-980, 1977.Crossref 15. Kendell RE, Gourlay J: The clinical distinction between the affective psychoses and schizophrenia . Br J Psychiatry 117:261-266, 1970. 16. Brockington IF, Kendell RE, Wainwright S, et al: The distinction between the affective psychoses and schizophrenia . Br J Psychiatry 135:243-248, 1979.Crossref 17. Carpenter WT Jr, Strauss JS, Bartko JJ: Flexible system for the diagnosis of schizophrenia: Report from the WHO International Pilot Study of Schizophrenia . Science 182:1275-1278, 1973.Crossref 18. Fowler RC, Liskow BI, Tanna VL, et al: Psychiatric illness and alcoholism . Alcoholism 1:125-128, 1977.Crossref 19. Dixon WJ (ed): Biomedical Computer Programs . Berkeley, University of California Press, 1977, pp 711-740. 20. Lachenbruch PA, Mickey MR: Estimation of error rates in discriminant analysis . Technometrics 10:1-11, 1968.Crossref 21. Carey G, Gottesman II: Reliability and validity in binary ratings: Areas of common misunderstanding in diagnosis and symptom ratings . Arch Gen Psychiatry 35:1454-1459, 1978.Crossref 22. Fleiss JL, Spitzer RL, Cohen J, et al: Three computer diagnosis methods compared . Arch Gen Psychiatry 27:643-649, 1972.Crossref 23. Melrose JP, Stroebel CF, Glueck BC: Diagnosis of psychopathology using stepwise multiple discriminant analysis . Compr Psychiatry 11:43-50, 1970.Crossref

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Jul 1, 1980

References