Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Scanning Microdensitometry of Optic Disc Pallor in Glaucoma

Scanning Microdensitometry of Optic Disc Pallor in Glaucoma Abstract • A scanning microdensitometric technique has been developed for measuring the optical density of black and white photographs of the optic disc. From the frequency distribution curve of all the densities of the whole area of the optic disc, a separate peak was identified as corresponding to the area of pallor of the optic disc. Areas of pallor were measured as percentage of areas of the total disc for normal, ocular hypertensive, open-angle glaucoma patients, and those with suspect discs. Median values of percent area of pallor showed correspondence with the clinical diagnosis, the glaucoma patients having significantly larger areas than the normal subjects. The microdensitometric technique provides an objective means of measuring the amount of optic disc pallor. It has potential usefulness for screening and for following up suspect and confirmed glaucomas to determine progression of the disease. (Arch Ophthalmol 95:2159-2165, 1977) References 1. Schwartz B: Cupping and pallor of the optic disc . Arch Ophthalmol 89:272-277, 1973.Crossref 2. Schwartz B: New techniques for the estimation of the optic disc and their clinical application . Trans Am Acad Ophthalmol Otolaryngol 81:OP227-237, 1976. 3. Schwartz B, Reinstein N, Leiberman D: Pallor of the optic disc: A quantitative photographic evaluation . Arch Ophthalmol 89:278-286, 1973.Crossref 4. Drance SM: Visual field defects in glaucoma in Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975,pp 190-209. 5. Siegel S: Non-Parametric Statistics for the Behavioral Sciences . New York, McGraw Hill Book Co Inc, 1956. 6. Parrin PH: The photographic emulsion , in Kingslake R (ed): Applied Optics and Engineering: The Detection of Light and Infrared Radiation . New York, Academic Press Inc, 1965, vol 2, pp 119-164. 7. Neurath P: A review of image processing in biology and medicine . Med Res Engin 10:9-15, 1971. 8. Swinson RA, Willes RL: Image analysis in medicine: Application of optical instrumentation in medicine . Proc Soc Photo Instr Engin 35:67-74, 1973. 9. Brown N: Quantitative slit-image photography of the lens . Trans Ophthalmol Soc UK 92:303-317, 1972. 10. Niesel P, Rokos L: Der Abspaltungsstreifen in der Spaltlampenphotographie der Linse bei Augenerkrankungen . Graefes Arch Klin Ophthalmol 199:21-29, 1976.Crossref 11. Boyd TAS, Rosen ES: A new method of clinical assessment of an intraocular pressure sensitive ischemic mechanism in glaucoma . Can J Ophthalmol 5:12-15, 1970. 12. Rosen ES, Boyd TAS: A new method of assessing choroidal ischemia in open-angle glaucoma and ocular hypertension . Am J Ophthalmol 70:912-921, 1970. 13. Donaldson A, Suckling RD: Examination of fluorescein retinal photography by scanning microdensitometry . J Biol Photo Assoc 38:75-78, 1970. 14. Suckling RD, Donaldson A: Densitometry of fluorescein angiography . Trans Ophthalmol Soc NZ 23:43-47, 1971. 15. Bulpitt CJ, Dollery CT: Estimation of retinal blood flow by measurement of the mean circulation time . J Cardiovasc Res 5:406-412, 1971.Crossref 16. Begg IS, Goldman H: The development of a technique for the densitometric analysis of fluorescein angiograms . Can J Ophthalmol 7:63-67, 1972. 17. Schwartz B, Fishbein SL: Densitometric analysis of blood flow of the optic nerve head in glaucoma . Proc Soc Photo Instr Engin 40:3-10, 1973. 18. Hill DW, Griffiths JD, Young S: Retinal blood flow measured by fluorescence angiography . Trans Ophthalmol Soc UK 93:325-331, 1973. 19. Farofonova TI, Balishinskaya TI, Babich PA, et al: On procedures employed in densitometric scanning of fluorescent angiograms . Vestnik Oftal , 1974, pp 66-68. 20. Shiose Y: Quantitative analysis of the optic cups using a photopattern analyser . Folia Ophthalmol Jap 24:54-60, 1973. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Scanning Microdensitometry of Optic Disc Pallor in Glaucoma

Archives of Ophthalmology , Volume 95 (12) – Dec 1, 1977

Loading next page...
 
/lp/american-medical-association/scanning-microdensitometry-of-optic-disc-pallor-in-glaucoma-zLhO103c2f
Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1977.04450120065005
Publisher site
See Article on Publisher Site

Abstract

Abstract • A scanning microdensitometric technique has been developed for measuring the optical density of black and white photographs of the optic disc. From the frequency distribution curve of all the densities of the whole area of the optic disc, a separate peak was identified as corresponding to the area of pallor of the optic disc. Areas of pallor were measured as percentage of areas of the total disc for normal, ocular hypertensive, open-angle glaucoma patients, and those with suspect discs. Median values of percent area of pallor showed correspondence with the clinical diagnosis, the glaucoma patients having significantly larger areas than the normal subjects. The microdensitometric technique provides an objective means of measuring the amount of optic disc pallor. It has potential usefulness for screening and for following up suspect and confirmed glaucomas to determine progression of the disease. (Arch Ophthalmol 95:2159-2165, 1977) References 1. Schwartz B: Cupping and pallor of the optic disc . Arch Ophthalmol 89:272-277, 1973.Crossref 2. Schwartz B: New techniques for the estimation of the optic disc and their clinical application . Trans Am Acad Ophthalmol Otolaryngol 81:OP227-237, 1976. 3. Schwartz B, Reinstein N, Leiberman D: Pallor of the optic disc: A quantitative photographic evaluation . Arch Ophthalmol 89:278-286, 1973.Crossref 4. Drance SM: Visual field defects in glaucoma in Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975,pp 190-209. 5. Siegel S: Non-Parametric Statistics for the Behavioral Sciences . New York, McGraw Hill Book Co Inc, 1956. 6. Parrin PH: The photographic emulsion , in Kingslake R (ed): Applied Optics and Engineering: The Detection of Light and Infrared Radiation . New York, Academic Press Inc, 1965, vol 2, pp 119-164. 7. Neurath P: A review of image processing in biology and medicine . Med Res Engin 10:9-15, 1971. 8. Swinson RA, Willes RL: Image analysis in medicine: Application of optical instrumentation in medicine . Proc Soc Photo Instr Engin 35:67-74, 1973. 9. Brown N: Quantitative slit-image photography of the lens . Trans Ophthalmol Soc UK 92:303-317, 1972. 10. Niesel P, Rokos L: Der Abspaltungsstreifen in der Spaltlampenphotographie der Linse bei Augenerkrankungen . Graefes Arch Klin Ophthalmol 199:21-29, 1976.Crossref 11. Boyd TAS, Rosen ES: A new method of clinical assessment of an intraocular pressure sensitive ischemic mechanism in glaucoma . Can J Ophthalmol 5:12-15, 1970. 12. Rosen ES, Boyd TAS: A new method of assessing choroidal ischemia in open-angle glaucoma and ocular hypertension . Am J Ophthalmol 70:912-921, 1970. 13. Donaldson A, Suckling RD: Examination of fluorescein retinal photography by scanning microdensitometry . J Biol Photo Assoc 38:75-78, 1970. 14. Suckling RD, Donaldson A: Densitometry of fluorescein angiography . Trans Ophthalmol Soc NZ 23:43-47, 1971. 15. Bulpitt CJ, Dollery CT: Estimation of retinal blood flow by measurement of the mean circulation time . J Cardiovasc Res 5:406-412, 1971.Crossref 16. Begg IS, Goldman H: The development of a technique for the densitometric analysis of fluorescein angiograms . Can J Ophthalmol 7:63-67, 1972. 17. Schwartz B, Fishbein SL: Densitometric analysis of blood flow of the optic nerve head in glaucoma . Proc Soc Photo Instr Engin 40:3-10, 1973. 18. Hill DW, Griffiths JD, Young S: Retinal blood flow measured by fluorescence angiography . Trans Ophthalmol Soc UK 93:325-331, 1973. 19. Farofonova TI, Balishinskaya TI, Babich PA, et al: On procedures employed in densitometric scanning of fluorescent angiograms . Vestnik Oftal , 1974, pp 66-68. 20. Shiose Y: Quantitative analysis of the optic cups using a photopattern analyser . Folia Ophthalmol Jap 24:54-60, 1973.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Dec 1, 1977

References