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Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL

Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a... ORIGINAL INVESTIGATION LESS IS MORE Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL Yu-Hsuan Shao, PhD; Peter C. Albertsen, MD; Calpurnyia B. Roberts, PhD; Yong Lin, PhD; Amit R. Mehta, MD; Mark N. Stein, MD; Robert S. DiPaola, MD; Grace L. Lu-Yao, PhD Background: Despite controversy over the benefit of PSA levels lower than 4.0 ng/mL harbor low-risk dis- prostate-specific antigen (PSA) screening, little is known ease (stage, T2a, PSA level, 10 ng/mL, and Gleason about risk profiles and treatment patterns in men diag- score,6), but over 75% of them received RP or RT. Men nosed as having prostate cancer who have a PSA value with screen-detected prostate cancer and PSA values lower less than or equal to 4.0 ng/mL. than 4 ng/mL were 1.49 (95% confidence interval [CI], 1.38-1.62) and 1.39 (95% CI, 1.30-1.49) times more likely Methods: We used data from the Surveillance, Epide- to receive RP and RT, respectively, and were less miology, and End Results system to describe patient char- likely to have high-grade disease than men who had acteristics and treatment patterns in the cases of 123 934 non–screen-detected prostate cancer (OR, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL

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References (29)

Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.221
pmid
20660846
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION LESS IS MORE Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL Yu-Hsuan Shao, PhD; Peter C. Albertsen, MD; Calpurnyia B. Roberts, PhD; Yong Lin, PhD; Amit R. Mehta, MD; Mark N. Stein, MD; Robert S. DiPaola, MD; Grace L. Lu-Yao, PhD Background: Despite controversy over the benefit of PSA levels lower than 4.0 ng/mL harbor low-risk dis- prostate-specific antigen (PSA) screening, little is known ease (stage, T2a, PSA level, 10 ng/mL, and Gleason about risk profiles and treatment patterns in men diag- score,6), but over 75% of them received RP or RT. Men nosed as having prostate cancer who have a PSA value with screen-detected prostate cancer and PSA values lower less than or equal to 4.0 ng/mL. than 4 ng/mL were 1.49 (95% confidence interval [CI], 1.38-1.62) and 1.39 (95% CI, 1.30-1.49) times more likely Methods: We used data from the Surveillance, Epide- to receive RP and RT, respectively, and were less miology, and End Results system to describe patient char- likely to have high-grade disease than men who had acteristics and treatment patterns in the cases of 123 934 non–screen-detected prostate cancer (OR,

Journal

JAMA Internal Medicine – American Medical Association

Published: Jul 26, 2010

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