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Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction

Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction ORIGINAL CONTRIBUTION Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction Dennis O. Mook-Kanamori, MD, MSc Context Adverse environmental exposures lead to developmental adaptations in fe- tal life. The influences of maternal physical characteristics and lifestyle habits on first- Eric A. P. Steegers, MD, PhD trimester fetal adaptations and the postnatal consequences are not known. Paul H. Eilers, PhD Objective To determine the risk factors and outcomes associated with first- Hein Raat, MD, PhD trimester growth restriction. Albert Hofman, MD, PhD Design, Setting, and Participants Prospective evaluation of the associations of Vincent W. V. Jaddoe, MD, PhD maternal physical characteristics and lifestyle habits with first-trimester fetal crown to rump length in 1631 mothers with a known and reliable first day of their last ETAL DEVELOPMENTAL ADAPTA- menstrual period and a regular menstrual cycle. Subsequently, we assessed the tions due to adverse environ- associations of first-trimester fetal growth restriction with the risks of adverse birth mental exposures may affect the outcomes and postnatal growth acceleration until the age of 2 years. The study was based in Rotterdam, the Netherlands. Mothers were enrolled between 2001 and Fstructure, physiology, and func- tion of various organ systems leading to fetal growth restriction http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction

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Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2010.78
pmid
20145229
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction Dennis O. Mook-Kanamori, MD, MSc Context Adverse environmental exposures lead to developmental adaptations in fe- tal life. The influences of maternal physical characteristics and lifestyle habits on first- Eric A. P. Steegers, MD, PhD trimester fetal adaptations and the postnatal consequences are not known. Paul H. Eilers, PhD Objective To determine the risk factors and outcomes associated with first- Hein Raat, MD, PhD trimester growth restriction. Albert Hofman, MD, PhD Design, Setting, and Participants Prospective evaluation of the associations of Vincent W. V. Jaddoe, MD, PhD maternal physical characteristics and lifestyle habits with first-trimester fetal crown to rump length in 1631 mothers with a known and reliable first day of their last ETAL DEVELOPMENTAL ADAPTA- menstrual period and a regular menstrual cycle. Subsequently, we assessed the tions due to adverse environ- associations of first-trimester fetal growth restriction with the risks of adverse birth mental exposures may affect the outcomes and postnatal growth acceleration until the age of 2 years. The study was based in Rotterdam, the Netherlands. Mothers were enrolled between 2001 and Fstructure, physiology, and func- tion of various organ systems leading to fetal growth restriction

Journal

JAMAAmerican Medical Association

Published: Feb 10, 2010

References