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T. Okumura, H. Aruga, Hidenori Inohara, T. Matsunaga, H. Shiozaki, K. Kobayashi, K. Kubo, J. Yoshida (1993)
Endoscopic examination of the upper gastrointestinal tract for the presence of second primary cancers in head and neck cancer patients.Acta oto-laryngologica. Supplementum, 501
G. Postma (2006)
Transnasal esophagoscopyCurrent Opinion in Otolaryngology & Head and Neck Surgery, 14
W. Mcguirt (1982)
Panendoscopy as a screening examination for simultaneous primary tumors in head and neck cancer: A prospective sequential study and review of the literatureThe Laryngoscope, 92
R. Maisel, H. Vermeersch (1981)
Panendoscopy for Second Primaries in Head and Neck CancerAnnals of Otology, Rhinology & Laryngology, 90
J. Gluckman, J. Crissman, J. Donegan (1980)
Multicentric squamous-cell carcinoma of the upper aerodigestive tract.Head & neck surgery, 3 2
K. Hujala, J. Sipilä, R. Grénman (2004)
Panendoscopy and synchronous second primary tumors in head and neck cancer patientsEuropean Archives of Oto-Rhino-Laryngology and Head & Neck, 262
C. Chung, Li-Jen Liao, Wu-Chia Lo, Y. Chou, Y. Chang, Yu-Chin Lin, Wei-Fan Hsu, P. Shueng, Tzong‐Hsi Lee (2013)
Risk factors for second primary neoplasia of esophagus in newly diagnosed head and neck cancer patients: a case–control studyBMC Gastroenterology, 13
O. Möschler, T. Spahn, Christina Middelberg-Bisping, W. Grosse-Thie, Bernd Christoph, G. Kloeppel, M. Mueller (2006)
Chromoendoscopy Is a Valuable Tool for Screening of High-Risk Patients with Head and Neck Cancer for Early Detection of Esophageal CancerDigestion, 73
J. Koshiol, A. Kreimer (2010)
Lessons from Australia: Human Papillomavirus Is Not a Major Risk Factor for Esophageal Squamous Cell CarcinomaCancer Epidemiology, Biomarkers & Prevention, 19
J. Atkins, W. Keane, K. Young, L. Rowe (1984)
Value of panendoscopy in determination of second primary cancer. A study of 451 cases of head and neck cancer.Archives of otolaryngology, 110 8
A. Shoushtari, M. Meeneghan, G. Treharne, J. Reibel, P. Levine, C. Moskaluk, M. Jameson, P. Read (2010)
Clinical Nodal Staging of T1-2 Tonsillar Squamous Cell Carcinoma Stratified by p16 Status and Implications for Ipsilateral Neck IrradiationThe Cancer Journal, 16
M. Gapany (2011)
Complications of esophagoscopy in an academic training programYearbook of Otolaryngology-head and Neck Surgery, 2011
H. Scherübl, B. Lampe, S. Faiss, P. Däubler, P. Bohlmann, T. Plath, H. Foss, H. Scherer, A. Strunz, B. Hoffmeister, H. Stein, M. Zeitz, E. Riecken (2002)
Screening for oesophageal neoplasia in patients with head and neck cancerBritish Journal of Cancer, 86
A. Antonsson, D. Nancarrow, I. Brown, A. Green, P. Drew, D. Watson, N. Hayward, D. Whiteman (2010)
High-Risk Human Papillomavirus in Esophageal Squamous Cell CarcinomaCancer Epidemiology, Biomarkers & Prevention, 19
S. Shapshay, W. Hong, M. Fried, A. Sismanis, C. Vaughan, Strong Ms (1980)
Simultaneous Carcinomas of the Esophagus and Upper Aerodigestive TractOtolaryngology-Head and Neck Surgery, 88
David Shonka, A. Shoushtari, C. Thomas, C. Moskaluk, P. Read, J. Reibel, P. Levine, M. Jameson (2009)
Predicting residual neck disease in patients with oropharyngeal squamous cell carcinoma treated with radiation therapy: utility of p16 status.Archives of otolaryngology--head & neck surgery, 135 11
A. Shaha, E. Hoover, M. Mitrani, J. Marti, Y. Krespi (1988)
Synchronicity, multicentricity, and metachronicity of head and neck cancer.Head & neck surgery, 10 4
H. Kubba, Ekaterini Spinou, Denise Brown (2003)
Is Same-Day Discharge Suitable following Rigid Esophagoscopy? Findings in a Series of 655 CasesENT Journal, 82
Gordon Sun, O. Aliu, Nicholas Moloci, J. Mondschein, James Burke, R. Hayward (2014)
Association between hospital case volume and the use of bronchoscopy and esophagoscopy during head and neck cancer diagnostic evaluationCancer, 120
A. Chaturvedi, E. Engels, W. Anderson, M. Gillison (2008)
Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26 4
J. Davidson, R. Gilbert, J. Irish, I. Witterick, Dale Brown, D. Birt, J. Freeman, P. Gullane (2000)
The role of panendoscopy in the management of mucosal head and neck malignancy—A prospective evaluationHead & Neck, 22
Arthur Weaver, Susan Fleming, T. Knechtges, Donald Smith (1979)
Triple endoscopy: a neglected essential in head and neck cancer.Surgery, 86 3
M. Gapany (2011)
Esophageal pathology in patients after treatment for head and neck cancerYearbook of Otolaryngology-head and Neck Surgery, 2011
F. Cianfriglia, D. Gregorio, A. Manieri (1999)
Multiple primary tumours in patients with oral squamous cell carcinoma.Oral oncology, 35 2
E. Abemayor, D. Moore, D. Hanson (1988)
Identification of synchronous esophageal tumors in patients with head and neck cancerJournal of Surgical Oncology, 38
T. Grossman (1989)
The incidence and diagnosis of secondary esophageal carcinoma in the head and neck cancer patientThe Laryngoscope, 99
Wen-Lun Wang, Ching‐Tai Lee, Yi-Chia Lee, T. Hwang, Chih‐Chun Wang, Jau-Chung Hwang, C. Tai, Chi-Yang Chang, S. Tsai, Cheng-Ping Wang, J. Ko, Jaw-Town Lin (2011)
Risk factors for developing synchronous esophageal neoplasia in patients with head and neck cancerHead & Neck, 33
A. Shoushtari, M. Meeneghan, K. Sheng, C. Moskaluk, C. Thomas, J. Reibel, Paul Levine, M. Jameson, K. Keene, P. Read (2010)
Intensity‐modulated radiotherapy outcomes for oropharyngeal squamous cell carcinoma patients stratified by p16 statusCancer, 116
M. Muto, S. Hironaka, Mari Nakane, N. Boku, A. Ohtsu, S. Yoshida (2002)
Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer.Gastrointestinal endoscopy, 56 4
E. Guardiola, X. Pivot, O. Dassonville, G. Poissonnet, P. Marcy, J. Otto, M. Poudenx, E. François, R. Bensadoun, A. Thyss, F. Demard, M. Schneider (2004)
Is routine triple endoscopy for head and neck carcinoma patients necessary in light of a negative chest computed tomography scan?Cancer, 101
U. Atabek, Mohit-Tabatabai Ma, Benjamin Rush, M. Ohanian, P. Rovelli (1990)
Impact of esophageal screening in patients with head and neck cancer.The American surgeon, 56 5
A. Cohn, S. Peppard (1980)
Multiple primary malignant tumors of the head and neck.American journal of otolaryngology, 1 5
L. Brown, S. Devesa (2002)
Epidemiologic trends in esophageal and gastric cancer in the United States.Surgical oncology clinics of North America, 11 2
J. Parker, James Hill (1988)
Panendoscopy in screening for synchronous primary malignanciesThe Laryngoscope, 98
M. Gapany (2012)
Role of panendoscopy to identify synchronous second primary malignancies in patients with oral cavity and oropharyngeal squamous cell carcinomaYearbook of Otolaryngology-head and Neck Surgery, 2012
Sachiko Tanaka, Y. Hirabayashi (2006)
International comparisons of cumulative risk of oesophagus cancer, from cancer incidence in five continents Vol. VIII.Japanese journal of clinical oncology, 36 9
I. Dhooge, M. Vos, F. Albers, P. Cauwenberge (2004)
Panendoscopy as a screening procedure for simultaneous primary tumors in head and neck cancerEuropean Archives of Oto-Rhino-Laryngology, 253
B. Leipzig, J. Zellmer, D. Klug (1985)
The role of endoscopy in evaluating patients with head and neck cancer. A multi-institutional prospective study.Archives of otolaryngology, 111 9
K. Strobel, S. Haerle, S. Stoeckli, Madeleine Schrank, J. Soyka, P. Veit-Haibach, T. Hany (2009)
Head and neck squamous cell carcinoma (HNSCC) – detection of synchronous primaries with 18F-FDG-PET/CTEuropean Journal of Nuclear Medicine and Molecular Imaging, 36
Kunal Jain, A. Sikora, S. Baxi, L. Morris (2013)
Synchronous cancers in patients with head and neck cancerCancer, 119
H. Ina, H. Shibuya, I. Ohashi, M. Kitagawa (1994)
The frequency of a concomitant early esophageal cancer in male patients with oral and oropharyngeal cancer. Screening results using lugol dye endoscopyCancer, 73
T. Chow, Daniel Lee, Chi‐Yee Choi, T. Chan, S. Lam (2009)
Prediction of simultaneous esophageal lesions in head and neck squamous cell carcinoma: a multivariate analysis.Archives of otolaryngology--head & neck surgery, 135 9
L. Brown, S. Devesa, W. Chow (2008)
Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age.Journal of the National Cancer Institute, 100 16
D. Schuller, M. Fritsch (1986)
An assessment of the value of triple endoscopy in the evaluation of head and neck cancer patientsJournal of Surgical Oncology, 32
S. Stoeckli, R. Zimmermann, S. Schmid (2001)
Role of Routine Panendoscopy in Cancer of the Upper Aerodigestive TractOtolaryngology–Head and Neck Surgery, 124
L. Morris, A. Sikora, S. Patel, R. Hayes, I. Ganly (2011)
Second primary cancers after an index head and neck cancer: subsite-specific trends in the era of human papillomavirus-associated oropharyngeal cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 29 6
C. Hashimoto, K. Iriya, Elisa Baba, T. Navarro-Rodriguez, M. Zerbini, J. Eisig, R. Barbuti, D. Chinzon, J. Moraes-Filho (2005)
Lugol's Dye Spray Chromoendoscopy Establishes Early Diagnosis of Esophageal Cancer in Patients with Primary Head and Neck CancerThe American Journal of Gastroenterology, 100
A. Tincani, N. Brandalise, A. Altemani, R. Scanavini, J. Valério, H. Lage, Giulianno Molina, A. Martins (2000)
Diagnosis of superficial esophageal cancer and dysplasia using endoscopic screening with a 2% lugol dye solution in patients with head and neck cancerHead & Neck, 22
S. Contini, G. Consigli, F. Lecce, Matteo Chiapasco, T. Ferri, P. Orsi (1991)
Vital staining of oesophagus in patients with head and neck cancer: still a worthwhile procedure.The Italian journal of gastroenterology, 23 1
G. Postma, Jacob Cohen, P. Belafsky, Stacey Halum, Sumeer Gupta, Kevin Bach, J. Koufman (2005)
Transnasal Esophagoscopy: Revisited (over 700 Consecutive Cases)The Laryngoscope, 115
Yan‐Ye Su, Wei-Chih Chen, H. Chuang, Chau-Shiang Guo, Yu-Tsai Lin, S. Luo, F. Fang, C. Chien (2013)
Effect of routine esophageal screening in patients with head and neck cancer.JAMA otolaryngology-- head & neck surgery, 139 4
A. Zaman, M. Hahn, R. Hapke, K. Knigge, M. Fennerty, R. Katon (1999)
A randomized trial of peroral versus transnasal unsedated endoscopy using an ultrathin videoendoscope.Gastrointestinal endoscopy, 49 3 Pt 1
C. Jackson (2007)
Bronchoscopy and Esophagoscopy: A Manual of Peroral Endoscopy and Laryngeal Surgery
ImportanceRigid esophagoscopy (RE) was once an essential part of the evaluation of patients with head and neck squamous cell carcinoma (HNSCC) due to the high likelihood of identifying a synchronous malignant neoplasm in the esophagus. Given recent advances in imaging and endoscopic techniques and changes in the incidence of esophageal cancer, the current role for RE in HNSCC staging is unclear. ObjectiveTo analyze the current role of RE in evaluating patients with HNSCC, and to determine the incidence of synchronous esophageal malignant neoplasms in patients with HNSCC. Design, Setting, and ParticipantsIn this retrospective study performed at an academic tertiary care center, 582 patients were studied who had undergone RE for HNSCC staging from July 1, 2004, through October 31, 2012. To assess the incidence of synchronous esophageal malignant neoplasms, a literature review was performed, and the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) data set was queried. Main Outcomes and MeasuresThe primary outcome measure was the incidence of synchronous esophageal malignant neoplasms, as measured by retrospective review at our institution, SEER data set analysis, and literature review. Secondary outcome measures were RE complications and nonmalignant findings during RE. ResultsA total of 601 staging REs were performed in 582 patients. The mean age was 60.2 years and 454 (78.0%) were men. There were 9 complications (1.5%), including 1 esophageal perforation (0.2%). Rigid esophagoscopy was aborted in 50 cases. Of the 551 completed REs, no abnormal findings were noted in 523 patients (94.9%), and nonmalignant pathologic findings were identified in 28 patients (5.1%). No synchronous primary esophageal carcinomas were detected. The incidence of synchronous esophageal malignant neoplasms found on screening endoscopy based on literature review and on SEER data set analysis was very low and has decreased from 1980 to 2010 in North America. The incidence reported in South America and Asia was relatively high. Conclusions and RelevanceRigid esophagoscopy is safe, but the utility is low for cancer staging and for detection of nonmalignant esophageal disease. Review of the literature and analysis of a large national cancer data set indicate that the incidence of synchronous esophageal malignant neoplasms in patients with HNSCC is low and has been decreasing during the past 3 decades. Thus, screening esophagoscopy should be limited to patients with HNSCC who are at high risk for synchronous esophageal malignant neoplasms.
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Jan 1, 2016
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