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Ribavirin Therapy of Adult Respiratory Syncytial Virus Pneumonitis

Ribavirin Therapy of Adult Respiratory Syncytial Virus Pneumonitis Abstract Respiratory syncytial virus is a common respiratory tract pathogen in infants. Pulmonary infection in adult and elderly populations can occur with severe and even fatal pneumonitis having been reported in several recent out-breaks. We present a previously healthy adult patient who developed respiratory syncytial virus pneumonia severe enough to require mechanical ventilation. Antiviral therapy with aerosolized ribavirin was successfully undertaken and the patient recovered completely. Respiratory syncytial virus infection should be considered in the differential diagnosis of atypical adult pneumonias. Aerosolized ribavirin therapy may be beneficial in treatment. (Arch Intern Med. 1991;151:2303-2304) References 1. Hart RCJ. An outbreak of respiratory syncytial virus infection in an old people's home . J Infect. 1984;8:259-261.Crossref 2. Mandel SK, Joglekav VM, Khan AS. An outbreak of respiratory syncytial virus infection in a continuing-care geriatric ward . Age Aging. 1985;14:184-186.Crossref 3. Sorvillo FJ, Huie SF, Strassburg MA, Butsumyo A, Shandera WX, Fannin SL. An outbreak of respiratory syncytial virus pneumonia in a nursing home for the elderly . J Infect. 1984;9:252-256.Crossref 4. Leuenson RM, Kantor OS. Fatal pneumonia in an adult due to respiratory syncytial virus . Arch Intern Med. 1987;147:791-792.Crossref 5. Rodriguez WJ, Parrott RH. Ribavirin aerosol treatment of respiratory syncytial virus infection in infants . Infect Dis Clin North Am. 1987;1:425-439. 6. Hall CB, McBride J, Watch E, et al. Aerosolized ribavirin treatment of infants with respiratory syncytial virus infection . N Engl J Med. 1983;308:1443-1447.Crossref 7. Vikerfors T, Grandion M, Olsen P. Respiratory syncytial virus infections in adults . Am Rev Respir Dis. 1987;136:561-564.Crossref 8. Smith RA, Knight V, Smith JAD, eds. Clinical Applications of Ribavirin . Orlando, Fla: Academic Press Inc; 1984:19-38. 9. Knight V, McClung HW, Wilson SZ, et al. Ribavirin small particle aerosol treatment in influenza . Lancet. 1981;2:945.Crossref 10. Hall CB, McBride JT, Walsh EE, et al. Ribavirin in the treatment of respiratory syncytial viral infections . In: Clinical Applications of Ribavirin . Orlando, Fla: Academic Press Inc; 1984:165-172. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Ribavirin Therapy of Adult Respiratory Syncytial Virus Pneumonitis

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Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1991.00400110139027
Publisher site
See Article on Publisher Site

Abstract

Abstract Respiratory syncytial virus is a common respiratory tract pathogen in infants. Pulmonary infection in adult and elderly populations can occur with severe and even fatal pneumonitis having been reported in several recent out-breaks. We present a previously healthy adult patient who developed respiratory syncytial virus pneumonia severe enough to require mechanical ventilation. Antiviral therapy with aerosolized ribavirin was successfully undertaken and the patient recovered completely. Respiratory syncytial virus infection should be considered in the differential diagnosis of atypical adult pneumonias. Aerosolized ribavirin therapy may be beneficial in treatment. (Arch Intern Med. 1991;151:2303-2304) References 1. Hart RCJ. An outbreak of respiratory syncytial virus infection in an old people's home . J Infect. 1984;8:259-261.Crossref 2. Mandel SK, Joglekav VM, Khan AS. An outbreak of respiratory syncytial virus infection in a continuing-care geriatric ward . Age Aging. 1985;14:184-186.Crossref 3. Sorvillo FJ, Huie SF, Strassburg MA, Butsumyo A, Shandera WX, Fannin SL. An outbreak of respiratory syncytial virus pneumonia in a nursing home for the elderly . J Infect. 1984;9:252-256.Crossref 4. Leuenson RM, Kantor OS. Fatal pneumonia in an adult due to respiratory syncytial virus . Arch Intern Med. 1987;147:791-792.Crossref 5. Rodriguez WJ, Parrott RH. Ribavirin aerosol treatment of respiratory syncytial virus infection in infants . Infect Dis Clin North Am. 1987;1:425-439. 6. Hall CB, McBride J, Watch E, et al. Aerosolized ribavirin treatment of infants with respiratory syncytial virus infection . N Engl J Med. 1983;308:1443-1447.Crossref 7. Vikerfors T, Grandion M, Olsen P. Respiratory syncytial virus infections in adults . Am Rev Respir Dis. 1987;136:561-564.Crossref 8. Smith RA, Knight V, Smith JAD, eds. Clinical Applications of Ribavirin . Orlando, Fla: Academic Press Inc; 1984:19-38. 9. Knight V, McClung HW, Wilson SZ, et al. Ribavirin small particle aerosol treatment in influenza . Lancet. 1981;2:945.Crossref 10. Hall CB, McBride JT, Walsh EE, et al. Ribavirin in the treatment of respiratory syncytial viral infections . In: Clinical Applications of Ribavirin . Orlando, Fla: Academic Press Inc; 1984:165-172.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Nov 1, 1991

References