Reye Syndrome and Aspirin Therapy
Abstract
Abstract Sir.—A significant number of children require long-term aspirin therapy for collagen vascular disorders, rheumatic fever, and other inflammatory diseases. Several cases of Reye syndrome (RS) have recently been documented in these children, who may actually be at an increased risk to develop the syndrome.1 Although reports indicate a decline in the incidence of acute rheumatic fever (ARF),2 a recent dramatic resurgence of ARF has occurred in Utah. This resurgence is reflected in...