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CLINICAL SCIENCES Retinopathy and Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort (CRIC) Study Juan E. Grunwald, MD; Judith Alexander, BA; Gui-Shuang Ying, PhD; Maureen Maguire, PhD; Ebenezer Daniel, PhD; Revell Whittock-Martin, BA; Candace Parker, BA; Kathleen McWilliams, CCRP; Joan C. Lo, MD; Alan Go, MD; Raymond Townsend, MD; Crystal A. Gadegbeku, MD; James P. Lash, MD; Jeffrey C. Fink, MD; Mahboob Rahman, MD, MS; Harold Feldman, MD, MSCE; John W. Kusek, PhD; Dawei Xie, PhD; Bernard G. Jaar, MD; for the CRIC Study Group Objective: To investigate the association between reti- Results: Greater severity of retinopathy was associated nopathy and chronic kidney disease. with lower estimated glomerular filtration rate after adjustment for traditional and nontraditional risk fac- Methods: In this observational, cross-sectional study, 2605 tors. The presence of vascular abnormalities usually patients of the Chronic Renal Insufficiency Cohort (CRIC) associated with hypertension was also associated with study, a multicenter study of chronic kidney disease, were lower estimated glomerular filtration rate. We found no offered participation. Nonmydriatic fundus photographs strong direct relationship between estimated glomerular of the disc and macula in both eyes were obtained in 1936 filtration rate and average arteriolar or venular calibers. of these subjects.
JAMA Ophthalmology – American Medical Association
Published: Sep 1, 2012
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