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Retinal Pigment Epithelial Tears Through the Fovea With Preservation of Good Visual Acuity

Retinal Pigment Epithelial Tears Through the Fovea With Preservation of Good Visual Acuity Abstract To the Editor. —Bressler et al1 raise the interesting question as to whether visual function can be maintained if pigment epithelium is lacking. The authors present two cases in which a large pigment epithelium rip underlying the fovea did not reduce central visual acuity to worse than 20/40 and 20/32.The authors seem to favor the speculation that "macular RPE [retinal pigment epithelium] may not be essential for maintenance of central vision." They do also mention that "foveal photoreceptors may be apposed to RPE that was not visible biomicroscopically or angiographically."We have performed experimental work that would favor the latter explanation.2 When the retina and pigment epithelium are removed experimentally, a profuse leakage of fluorescein occurs through bare Bruch's membrane into the vitreous cavity. This leakage terminates quickly because of a thin layer of unpigmented cells covering the defect. Such profuse leakage has been observed in human References 1. Bressler NM, Finklestein D, Sunness JS, Maguire AM, Yarian D. Retinal pigment epithelial tears through the fovea with preservation of good visual acuity . Arch Ophthalmol . 1990;108:1694-1697.Crossref 2. Heriot WJ, Machemer R. Pigment epithelial repair. Graefes Arch Clin Exp Ophthalmol. In press. 3. Sunakawa M, Tsukahara I. Tears of the retinal pigment epithelium and serious retinal detachment . Am J Ophthalmol . 1985;100:488-489. 4. Swanson DE, Kalina RE, Guzak St V. Tears of the retinal pigment epithelium: occurrence in retinal detachments and/or chorioretinal scars . Retina . 1984;4:115-118.Crossref 5. Murphy RP, Yeo JH, Green WR, Patz A. Dehiscenses of the pigment epithelium . Trans Am Ophthalmol Soc . 1985;83:63-79. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Retinal Pigment Epithelial Tears Through the Fovea With Preservation of Good Visual Acuity

Archives of Ophthalmology , Volume 109 (11) – Nov 1, 1991

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Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1991.01080110026009
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor. —Bressler et al1 raise the interesting question as to whether visual function can be maintained if pigment epithelium is lacking. The authors present two cases in which a large pigment epithelium rip underlying the fovea did not reduce central visual acuity to worse than 20/40 and 20/32.The authors seem to favor the speculation that "macular RPE [retinal pigment epithelium] may not be essential for maintenance of central vision." They do also mention that "foveal photoreceptors may be apposed to RPE that was not visible biomicroscopically or angiographically."We have performed experimental work that would favor the latter explanation.2 When the retina and pigment epithelium are removed experimentally, a profuse leakage of fluorescein occurs through bare Bruch's membrane into the vitreous cavity. This leakage terminates quickly because of a thin layer of unpigmented cells covering the defect. Such profuse leakage has been observed in human References 1. Bressler NM, Finklestein D, Sunness JS, Maguire AM, Yarian D. Retinal pigment epithelial tears through the fovea with preservation of good visual acuity . Arch Ophthalmol . 1990;108:1694-1697.Crossref 2. Heriot WJ, Machemer R. Pigment epithelial repair. Graefes Arch Clin Exp Ophthalmol. In press. 3. Sunakawa M, Tsukahara I. Tears of the retinal pigment epithelium and serious retinal detachment . Am J Ophthalmol . 1985;100:488-489. 4. Swanson DE, Kalina RE, Guzak St V. Tears of the retinal pigment epithelium: occurrence in retinal detachments and/or chorioretinal scars . Retina . 1984;4:115-118.Crossref 5. Murphy RP, Yeo JH, Green WR, Patz A. Dehiscenses of the pigment epithelium . Trans Am Ophthalmol Soc . 1985;83:63-79.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Nov 1, 1991

References