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RESULTS FOLLOWING THE ADMINISTRATION OF ALKALI PHOSPHATES TO SPASMOPHILIC, RACHITIC AND NORMAL INFANTS

RESULTS FOLLOWING THE ADMINISTRATION OF ALKALI PHOSPHATES TO SPASMOPHILIC, RACHITIC AND NORMAL... Considerable research has been conducted recently, investigating the influence of the alkali phosphates, especially sodium and potassium diortho-phosphates, on normal and spasmophilic infants. Binger1 produced tetany by the intravenous injection of ortho-phosphates. Howland and Marriott2 found that when the inorganic phosphorus of the serum was high in severe nephritis that the calcium of the serum was greatly diminished. They considered the question, therefore, whether there was a sufficient accumulation of inorganic phosphates in the serum in tetany to account for the reduction of the calcium. Their determinations in cases of active tetany showed a low calcium content in the blood serum but no significant increase in phosphorus. Kramer, Tisdall and Howland2a have very recently confirmed this work and state that an increase in the inorganic phosphorus of the serum does not seem to be responsible for infantile tetany, although in cases of rickets complicated by tetany there http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

RESULTS FOLLOWING THE ADMINISTRATION OF ALKALI PHOSPHATES TO SPASMOPHILIC, RACHITIC AND NORMAL INFANTS

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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1922 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1922.01910390057004
Publisher site
See Article on Publisher Site

Abstract

Considerable research has been conducted recently, investigating the influence of the alkali phosphates, especially sodium and potassium diortho-phosphates, on normal and spasmophilic infants. Binger1 produced tetany by the intravenous injection of ortho-phosphates. Howland and Marriott2 found that when the inorganic phosphorus of the serum was high in severe nephritis that the calcium of the serum was greatly diminished. They considered the question, therefore, whether there was a sufficient accumulation of inorganic phosphates in the serum in tetany to account for the reduction of the calcium. Their determinations in cases of active tetany showed a low calcium content in the blood serum but no significant increase in phosphorus. Kramer, Tisdall and Howland2a have very recently confirmed this work and state that an increase in the inorganic phosphorus of the serum does not seem to be responsible for infantile tetany, although in cases of rickets complicated by tetany there

Journal

American journal of diseases of children – American Medical Association

Published: Mar 1, 1922

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