Abstract In a case of actinomycotic mycetoma caused by Streptomyces madurae with extensive destruction of the bone, the foot was saved from amputation by appropriate antibiotic therapy given for a period of 2 1/2 years. Periodic x-ray examinations gave a valuable guide to the progress of the patient. Chemotherapy and antibiotics play an important role in the present day management of mycetoma. Cutaneous amelioration is not the criteria for cure. The bone restoration that occurs much later should be the guide for the duration of therapy. References 1. Kandhari KC, Mohapatra LN, Sehgal, et al: Black grain mycetoma foot . Arch Dermatol 89:867-870, 1964.Crossref 2. Desai SC, Pardanani DS, Sreedevi N, et al: Studies on mycetoma: Clinical, mycological, histological and radiological studies on 40 cases of mycetoma with a note on its history and epidemiology in India . Ind J Surg 32:427-447, 1970. 3. Kandhari KC, Girgla HS, Mohapatra LN, et al: Actinomycotic mycetoma . Arch Dermatol 104:686-687, 1971.Crossref 4. Koshi G, Victor N, Chacko J: Causal agents in mycetoma of the foot in Southern India . Sabouraudia 10:14-18, 1972.Crossref 5. Kamalam A, Mammen A, Premalatha S, et al: Norcardiosis—two case reports . Aust J Dermatol 13:69-74, 1972.Crossref 6. Emmons CW, Binford CH, Utz JP: The Mycetomas, Medical Mycology . Philadelphia, Lea & Febiger, pp 393 & 403, 1970. 7. Vanbreuseghem R: Early diagnosis, treatment, and epidemiology of mycetoma . Rev Med Vet Mycol 6:49-60, 1967. 8. Lynch JB: Mycetoma in the Sudan . Ann R Coll Surg 35:319-340, 1964. 9. Davies AGM: The bone changes of madura foot. Observations on Uganda Africans . Radiology 70:841-847, 1958.Crossref 10. Abbott P: Mycetoma in the Sudan . Trans R Soc Trop Med Hyg 50:11-24, 1956.Crossref 11. Zias N, Taplin D, Rebell G: Mycetoma . Arch Dermatol 99:215-225, 1969.Crossref 12. Desai SC, Pardanani DS, Kher YR, et al: Therapeutic investigations on Actinomycetoma . Ind J Surg 32:448-461, 1970.
Archives of Dermatology – American Medical Association
Published: Sep 1, 1975
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