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RESPIRATORY ANAPHYLAXIS

RESPIRATORY ANAPHYLAXIS Several years ago, one of us1 studied a group of children suffering from bronchial asthma, the cause of which was traced to rabbit hair. In none of these cases was it possible to obtain any hereditary evidence of protein sensitivity; the opinion was therefore expressed at that time that the sensitization had been acquired through the inhalation of dry dust resulting from the rabbit hair which was present in pillows, comfortables, toys, clothing and other articles. In order to prove this hypothesis, we felt it necessary to produce in an animal a state of protein sensitivity through the direct inhalation of a dry animal emanation, and, further, to reproduce the symptom-complex of bronchial asthma. MATERIALS AND METHODS USED In approaching this work, we were confronted with the following considerations: first, the choice of an animal in which this mechanism could be reproduced; second, the necessity of reproducing the entire http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

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References (20)

Publisher
American Medical Association
Copyright
Copyright © 1927 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1927.04130190030002
Publisher site
See Article on Publisher Site

Abstract

Several years ago, one of us1 studied a group of children suffering from bronchial asthma, the cause of which was traced to rabbit hair. In none of these cases was it possible to obtain any hereditary evidence of protein sensitivity; the opinion was therefore expressed at that time that the sensitization had been acquired through the inhalation of dry dust resulting from the rabbit hair which was present in pillows, comfortables, toys, clothing and other articles. In order to prove this hypothesis, we felt it necessary to produce in an animal a state of protein sensitivity through the direct inhalation of a dry animal emanation, and, further, to reproduce the symptom-complex of bronchial asthma. MATERIALS AND METHODS USED In approaching this work, we were confronted with the following considerations: first, the choice of an animal in which this mechanism could be reproduced; second, the necessity of reproducing the entire

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jul 1, 1927

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