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Renal Vein Thrombosis and the: Studies

Renal Vein Thrombosis and the: Studies Abstract THROMBOSIS of the renal veins associated with the nephrotic syndrome has been recognized since 1939.1 Since then, more than 50 cases have been reported and reviewed.2,3 While it is generally agreed that the renal vein thrombosis is responsible for the development of the nephrotic syndrome, the mechanism for the development of proteinuria is unclear and has received little attention. The demonstration of γ-globulin in the glomeruli and lung as described in the following report suggests that an immune mechanism may be involved. Report of a Case This 44-year-old man was well until three years prior to death when he had a myocardial infarction from which he recovered uneventfully. Six months prior to death, he noted ankle edema and was found to have proteinuria. He had no symptoms referable to his urinary system and had no symptoms of congestive heart failure. Physical examination three months prior to death References 1. Derow, H.A.; Schlesinger, M.J.; and Savitz, H.A.: Chronic Progressive Occlusion of the Inferior Vena Cava and Renal and Portal Veins, With a Clinical Picture of Nephrotic Syndrome , Arch Intern Med 63:626, 1939.Crossref 2. Pollak, V., et al: Renal Vein Thrombosis and the Nephrotic Syndrome , Amer J Med 21:496, 1956.Crossref 3. McCarthy, L.J.; Titus, J.L.; and Daugherty, G.W.: Bilateral Renal Vein Thrombosis and the Nephrotic Syndrome in Adults , Ann Intern Med 58:837, 1963.Crossref 4. Strauss, A.J.L., et al: Purification of Human Serum Gamma Globulin for Immunologic Studies , J Immun 93:24, 1964. 5. Wood, B.T.; Thompson, S.H.; and Goldstein, G.: Fluorescent Antibody Staining , J Immun 95: 225, 1965. 6. Vilk, N.L., cited by Harrison, C.V., et al: Clinical Aspects of Renal Vein Thrombosis , Quart J Med 25:285, 1956. 7. Weiser, M.M., and Owano, L.R.: Nephrotic Syndrome Secondary to Primary Amyloidosis With Terminal Bilateral Renal Vein Thrombosis , Univ Mich Med Bull 29:92, 1963. 8. Harrison, C.V.; Milne, M.D.; and Steiner, R.E.: Clinical Aspects of Renal Vein Thrombosis , Quart J Med 25:285, 1956. 9. Morris, J.F.; Ginn, H.E.; and Thompson, D.D.: Unilateral Renal Vein Thrombosis Associated With the Nephrotic Syndrome , Amer J Med 34:867, 1963.Crossref 10. Omae, T.; Masson, G.M.C.; and Corcoran, A.C.: Experimental Production of Nephrotic Syndrome , Proc Soc Exp Biol Med 97:821, 1958.Crossref 11. Panner, B.: Electronmicroscopy in a Case of Nephrotic Syndrome Due to Renal Vein Thrombosis , Arch Path 76:303, 1963. 12. Ehrenfeld, E.N.; Gery, I.; and Davies, A.M.: Specific Antibodies in Heart Disease , Lancet 1: 1138, 1961.Crossref 13. Baxter, J.H., and Goodman, H.C.: Nephrotoxic Serum Nephritis in Rats , J Exp Med 104:467,1956.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Renal Vein Thrombosis and the: Studies

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Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1967.00300050064010
Publisher site
See Article on Publisher Site

Abstract

Abstract THROMBOSIS of the renal veins associated with the nephrotic syndrome has been recognized since 1939.1 Since then, more than 50 cases have been reported and reviewed.2,3 While it is generally agreed that the renal vein thrombosis is responsible for the development of the nephrotic syndrome, the mechanism for the development of proteinuria is unclear and has received little attention. The demonstration of γ-globulin in the glomeruli and lung as described in the following report suggests that an immune mechanism may be involved. Report of a Case This 44-year-old man was well until three years prior to death when he had a myocardial infarction from which he recovered uneventfully. Six months prior to death, he noted ankle edema and was found to have proteinuria. He had no symptoms referable to his urinary system and had no symptoms of congestive heart failure. Physical examination three months prior to death References 1. Derow, H.A.; Schlesinger, M.J.; and Savitz, H.A.: Chronic Progressive Occlusion of the Inferior Vena Cava and Renal and Portal Veins, With a Clinical Picture of Nephrotic Syndrome , Arch Intern Med 63:626, 1939.Crossref 2. Pollak, V., et al: Renal Vein Thrombosis and the Nephrotic Syndrome , Amer J Med 21:496, 1956.Crossref 3. McCarthy, L.J.; Titus, J.L.; and Daugherty, G.W.: Bilateral Renal Vein Thrombosis and the Nephrotic Syndrome in Adults , Ann Intern Med 58:837, 1963.Crossref 4. Strauss, A.J.L., et al: Purification of Human Serum Gamma Globulin for Immunologic Studies , J Immun 93:24, 1964. 5. Wood, B.T.; Thompson, S.H.; and Goldstein, G.: Fluorescent Antibody Staining , J Immun 95: 225, 1965. 6. Vilk, N.L., cited by Harrison, C.V., et al: Clinical Aspects of Renal Vein Thrombosis , Quart J Med 25:285, 1956. 7. Weiser, M.M., and Owano, L.R.: Nephrotic Syndrome Secondary to Primary Amyloidosis With Terminal Bilateral Renal Vein Thrombosis , Univ Mich Med Bull 29:92, 1963. 8. Harrison, C.V.; Milne, M.D.; and Steiner, R.E.: Clinical Aspects of Renal Vein Thrombosis , Quart J Med 25:285, 1956. 9. Morris, J.F.; Ginn, H.E.; and Thompson, D.D.: Unilateral Renal Vein Thrombosis Associated With the Nephrotic Syndrome , Amer J Med 34:867, 1963.Crossref 10. Omae, T.; Masson, G.M.C.; and Corcoran, A.C.: Experimental Production of Nephrotic Syndrome , Proc Soc Exp Biol Med 97:821, 1958.Crossref 11. Panner, B.: Electronmicroscopy in a Case of Nephrotic Syndrome Due to Renal Vein Thrombosis , Arch Path 76:303, 1963. 12. Ehrenfeld, E.N.; Gery, I.; and Davies, A.M.: Specific Antibodies in Heart Disease , Lancet 1: 1138, 1961.Crossref 13. Baxter, J.H., and Goodman, H.C.: Nephrotoxic Serum Nephritis in Rats , J Exp Med 104:467,1956.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Dec 1, 1967

References