Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Renaissance of the Retinal Pigment Epithelium

Renaissance of the Retinal Pigment Epithelium Abstract THE APPLICATION of recent advances in laboratory methods to the study of individual intraocular structures has greatly enhanced our ability to evaluate their function in health and disease. Nowhere is this more apparent than in the investigation of the retinal pigment epithelium where the utilization of light and electron microscopy coupled with histochemistry and autoradiography has recently revealed unsuspected functions. Long associated with the storage of vitamin A and its conversion to a form that can be utilized by the photoreceptors for the synthesis of rhodopsin, the retinal pigment epithelium has now been found to play an important role in the phagocytosis and digestion of the rod outer segment discs as well as other retinal substances. In addition, the ability of the pigment epithelium to produce and excrete a portion of the mucoprotein which surrounds the outer segments of the photoreceptors is now generally accepted. The ultrastructural pathways for the References 1. Hogan MJ: Role of the retinal pigment epithelium in macular disease . Trans Amer Acad Ophthal Otolaryng 76:64, 1972. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Renaissance of the Retinal Pigment Epithelium

Spencer, William H.
Archives of Ophthalmology , Volume 88 (1) – Jul 1, 1972
Download PDF
1 page

Renaissance of the Retinal Pigment Epithelium

Abstract

Abstract THE APPLICATION of recent advances in laboratory methods to the study of individual intraocular structures has greatly enhanced our ability to evaluate their function in health and disease. Nowhere is this more apparent than in the investigation of the retinal pigment epithelium where the utilization of light and electron microscopy coupled with histochemistry and autoradiography has recently revealed unsuspected functions. Long associated with the storage of vitamin A and its...
Loading next page...
 
/lp/american-medical-association/renaissance-of-the-retinal-pigment-epithelium-YVNXGiMpvO

References (1)

Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1972.01000030003001
Publisher site
See Article on Publisher Site

Abstract

Abstract THE APPLICATION of recent advances in laboratory methods to the study of individual intraocular structures has greatly enhanced our ability to evaluate their function in health and disease. Nowhere is this more apparent than in the investigation of the retinal pigment epithelium where the utilization of light and electron microscopy coupled with histochemistry and autoradiography has recently revealed unsuspected functions. Long associated with the storage of vitamin A and its conversion to a form that can be utilized by the photoreceptors for the synthesis of rhodopsin, the retinal pigment epithelium has now been found to play an important role in the phagocytosis and digestion of the rod outer segment discs as well as other retinal substances. In addition, the ability of the pigment epithelium to produce and excrete a portion of the mucoprotein which surrounds the outer segments of the photoreceptors is now generally accepted. The ultrastructural pathways for the References 1. Hogan MJ: Role of the retinal pigment epithelium in macular disease . Trans Amer Acad Ophthal Otolaryng 76:64, 1972.

Journal

Archives of Ophthalmology – American Medical Association

Published: Jul 1, 1972

There are no references for this article.