Remitting Seronegative Symmetrical Synovitis With Pitting Edema
Abstract
To the Editor.—
The article by McCarty et al1 described ten elderly patients with an acute-onset seronegative symmetric synovitis associated with pitting edema of the hands and feet, which completely remitted over several months. The authors believe that these cases were representative of a distinctive syndrome and chose to call it "remitting seronegative symmetrical synovitis with pitting edema" (RS3PE syndrome). In their discussion, the authors postulate that an infectious...