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Remitting Seronegative Symmetrical Synovitis With Pitting Edema

Remitting Seronegative Symmetrical Synovitis With Pitting Edema To the Editor.— The article by McCarty et al1 described ten elderly patients with an acute-onset seronegative symmetric synovitis associated with pitting edema of the hands and feet, which completely remitted over several months. The authors believe that these cases were representative of a distinctive syndrome and chose to call it "remitting seronegative symmetrical synovitis with pitting edema" (RS3PE syndrome). In their discussion, the authors postulate that an infectious agent might trigger this syndrome in a genetically programmed host. We have recently seen a patient identical to that described by McCarty et al, in whom an infectious agent known to cause a reactive arthritis, Campylobacter jejuni, was isolated by routine stool culture.2 Report of a Case.— On Feb 4, 1985, a 62-year-old man began experiencing a sore throat, nausea, vomiting, an episode of diarrhea, and fever. On the morning of Feb 10, 1985, he awoke http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Remitting Seronegative Symmetrical Synovitis With Pitting Edema

JAMA , Volume 255 (18) – May 9, 1986

Remitting Seronegative Symmetrical Synovitis With Pitting Edema

Abstract



To the Editor.—
The article by McCarty et al1 described ten elderly patients with an acute-onset seronegative symmetric synovitis associated with pitting edema of the hands and feet, which completely remitted over several months. The authors believe that these cases were representative of a distinctive syndrome and chose to call it "remitting seronegative symmetrical synovitis with pitting edema" (RS3PE syndrome). In their discussion, the authors postulate that an infectious...
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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1986 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1986.03370180070018
Publisher site
See Article on Publisher Site

Abstract

To the Editor.— The article by McCarty et al1 described ten elderly patients with an acute-onset seronegative symmetric synovitis associated with pitting edema of the hands and feet, which completely remitted over several months. The authors believe that these cases were representative of a distinctive syndrome and chose to call it "remitting seronegative symmetrical synovitis with pitting edema" (RS3PE syndrome). In their discussion, the authors postulate that an infectious agent might trigger this syndrome in a genetically programmed host. We have recently seen a patient identical to that described by McCarty et al, in whom an infectious agent known to cause a reactive arthritis, Campylobacter jejuni, was isolated by routine stool culture.2 Report of a Case.— On Feb 4, 1985, a 62-year-old man began experiencing a sore throat, nausea, vomiting, an episode of diarrhea, and fever. On the morning of Feb 10, 1985, he awoke

Journal

JAMAAmerican Medical Association

Published: May 9, 1986

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