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Reflectance Confocal Microscopy and Features of Melanocytic Lesions

Reflectance Confocal Microscopy and Features of Melanocytic Lesions STUDY Reflectance Confocal Microscopy and Features of Melanocytic Lesions An Internet-Based Study of the Reproducibility of Terminology Giovanni Pellacani, MD; Marco Vinceti, MD; Sara Bassoli, MD; Ralph Braun, MD; Salvador Gonzalez, MD; Pascale Guitera, MD; Caterina Longo, MD; Ashfaq A. Marghoob, MD; Scott W. Menzies, MD; Susana Puig, MD; Alon Scope, MD; Stefania Seidenari, MD; Josep Malvehy, MD Objective: To test the interobserver and intraobserver Results: High overall levels of reproducibility were reproducibility of the standard terminology for descrip- shown for most of the evaluated features. In both the tion and diagnosis of melanocytic lesions in in vivo con- training and test sets there was a parallel trend of focal microscopy. decreasing  values as deeper anatomic skin levels were evaluated. All of the features, except 1, used for Design: A dedicated Web platform was developed to train melanoma diagnosis, including roundish pagetoid the participants and to allow independent distant evalu- cells, nonedged papillae, atypical cells in basal layer, ations of confocal images via the Internet. cerebriform clusters, and nucleated cells infiltrating dermal papillae, showed high overall levels of repro- Setting: Department of Dermatology, University of ducibility. However, less-than-ideal reproducibility Modena and Reggio Emilia, Modena, Italy. was obtained for http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/archdermatol.2009.228
pmid
19841401
Publisher site
See Article on Publisher Site

Abstract

STUDY Reflectance Confocal Microscopy and Features of Melanocytic Lesions An Internet-Based Study of the Reproducibility of Terminology Giovanni Pellacani, MD; Marco Vinceti, MD; Sara Bassoli, MD; Ralph Braun, MD; Salvador Gonzalez, MD; Pascale Guitera, MD; Caterina Longo, MD; Ashfaq A. Marghoob, MD; Scott W. Menzies, MD; Susana Puig, MD; Alon Scope, MD; Stefania Seidenari, MD; Josep Malvehy, MD Objective: To test the interobserver and intraobserver Results: High overall levels of reproducibility were reproducibility of the standard terminology for descrip- shown for most of the evaluated features. In both the tion and diagnosis of melanocytic lesions in in vivo con- training and test sets there was a parallel trend of focal microscopy. decreasing  values as deeper anatomic skin levels were evaluated. All of the features, except 1, used for Design: A dedicated Web platform was developed to train melanoma diagnosis, including roundish pagetoid the participants and to allow independent distant evalu- cells, nonedged papillae, atypical cells in basal layer, ations of confocal images via the Internet. cerebriform clusters, and nucleated cells infiltrating dermal papillae, showed high overall levels of repro- Setting: Department of Dermatology, University of ducibility. However, less-than-ideal reproducibility Modena and Reggio Emilia, Modena, Italy. was obtained for

Journal

JAMA DermatologyAmerican Medical Association

Published: Oct 1, 2009

References